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Right Ventricular Adaptation Is Associated with the Glu298Asp Variant of the NOS3 Gene in Elite Athletes

Nitric oxide (NO), an important endogenous pulmonary vasodilator is synthetized by the endothelial NO synthase (NOS3). Reduced NO bioavailability and thus the Glu298Asp polymorphism of NOS3 may enhance right ventricular (RV) afterload and hypertrophic remodeling and influence athletic performance. T...

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Detalles Bibliográficos
Autores principales:	Szelid, Zsolt, Lux, Árpád, Kolossváry, Márton, Tóth, Attila, Vágó, Hajnalka, Lendvai, Zsuzsanna, Kiss, Loretta, Maurovich-Horvat, Pál, Bagyura, Zsolt, Merkely, Béla
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627801/ https://www.ncbi.nlm.nih.gov/pubmed/26517550 http://dx.doi.org/10.1371/journal.pone.0141680

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