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Klotho Regulates 14-3-3ζ Monomerization and Binding to the ASK1 Signaling Complex in Response to Oxidative Stress

The reactive oxygen species (ROS)-sensitive apoptosis signal-regulating kinase 1 (ASK1) signaling complex is a key regulator of p38 MAPK activity, a major modulator of stress-associated with aging disorders. We recently reported that the ratio of free ASK1 to the complex-bound ASK1 is significantly...

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Detalles Bibliográficos
Autores principales:	Brobey, Reynolds K., Dheghani, Mehdi, Foster, Philip P., Kuro-o, Makoto, Rosenblatt, Kevin P
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627807/ https://www.ncbi.nlm.nih.gov/pubmed/26517365 http://dx.doi.org/10.1371/journal.pone.0141968

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