Urinary Retention, Incontinence, and Dysregulation of Muscarinic Receptors in Male Mice Lacking Mras

Here we show that male, but not female mice lacking expression of the GTPase M-Ras developed urinary retention with distention of the bladder that exacerbated with age but occurred in the absence of obvious anatomical outlet obstruction. There were changes in detrusor morphology in Mras (-/-) males:...

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Detalles Bibliográficos
Autores principales: Ehrhardt, Annette, Wang, Bin, Yung, Andrew C., Wang, Yanni, Kozlowski, Piotr, van Breemen, Cornelis, Schrader, John W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627820/
https://www.ncbi.nlm.nih.gov/pubmed/26516777
http://dx.doi.org/10.1371/journal.pone.0141493

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