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Development and validation of a LC–MS/MS method for quantification of hetrombopag for pharmacokinetics study

Hetrombopag as the derivative of ethylidene hydrazine carboxamide was recently developed into a novel patented non-peptide thrombopoietin mimetic and thrombopoietin receptor agonist to treat idiopathic thrombocytopenic purpura. To study the pharmacokinetics of hetrombopag, a highly sensitive, rapid...

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Detalles Bibliográficos
Autores principales:	Chen, Tao, Chen, Zhonghua, Zhang, Suxing, Zhang, Kezhi, Wang, Laiyou
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4628022/ https://www.ncbi.nlm.nih.gov/pubmed/26543786 http://dx.doi.org/10.1186/s40064-015-1446-0

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