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Independent Mechanisms Target SMCHD1 to Trimethylated Histone H3 Lysine 9-Modified Chromatin and the Inactive X Chromosome
The chromosomal protein SMCHD1 plays an important role in epigenetic silencing at diverse loci, including the inactive X chromosome, imprinted genes, and the facioscapulohumeral muscular dystrophy locus. Although homology with canonical SMC family proteins suggests a role in chromosome organization,...
Autores principales: | Brideau, Nicholas J., Coker, Heather, Gendrel, Anne-Valerie, Siebert, C. Alistair, Bezstarosti, Karel, Demmers, Jeroen, Poot, Raymond A., Nesterova, Tatyana B., Brockdorff, Neil |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4628070/ https://www.ncbi.nlm.nih.gov/pubmed/26391951 http://dx.doi.org/10.1128/MCB.00432-15 |
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