Next-generation sequencing identifies altered whole blood microRNAs in neuromyelitis optica spectrum disorder which may permit discrimination from multiple sclerosis

BACKGROUND: Neuromyelitis optica spectrum disorder (NMOSD) and multiple sclerosis (MS) have a similar clinical phenotype but represent distinct diseases, requiring different therapies. MicroRNAs (miRNAs) are short non-coding RNAs whose expression profiles can serve as diagnostic biomarkers and which...

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Detalles Bibliográficos
Autores principales: Keller, Andreas, Leidinger, Petra, Meese, Eckart, Haas, Jan, Backes, Christina, Rasche, Ludwig, Behrens, Janina R., Pfuhl, Catherina, Wakonig, Katharina, Gieß, René M., Jarius, Sven, Meder, Benjamin, Bellmann-Strobl, Judith, Paul, Friedemann, Pache, Florence C., Ruprecht, Klemens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4628234/
https://www.ncbi.nlm.nih.gov/pubmed/26521232
http://dx.doi.org/10.1186/s12974-015-0418-1

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