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Cytosolic phospholipase A(2) plays a crucial role in ROS/NO signaling during microglial activation through the lipoxygenase pathway
BACKGROUND: Oxidative stress and inflammation are important factors contributing to the pathophysiology of numerous neurological disorders, including Alzheimer’s disease, Parkinson’s disease, acute stroke, and infections of the brain. There is well-established evidence that proinflammatory cytokines...
Autores principales: | Chuang, Dennis Y., Simonyi, Agnes, Kotzbauer, Paul T., Gu, Zezong, Sun, Grace Y. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4628268/ https://www.ncbi.nlm.nih.gov/pubmed/26520095 http://dx.doi.org/10.1186/s12974-015-0419-0 |
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