Cargando…

Enhanced in vitro osteogenic differentiation of human fetal MSCs attached to 3D microcarriers versus harvested from 2D monolayers

BACKGROUND: Mesenchymal stem cells (MSCs) are of great interest in bone regenerative medicine due to their osteogenic potential and trophic effects. However, challenges to large-scale production of MSCs can hinder the translation of MSC therapies. 3D Microcarrier (MC)-based MSC culture presents a sc...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shekaran, Asha, Sim, Eileen, Tan, Kah Yong, Chan, Jerry Kok Yen, Choolani, Mahesh, Reuveny, Shaul, Oh, Steve
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4628389/ https://www.ncbi.nlm.nih.gov/pubmed/26520400 http://dx.doi.org/10.1186/s12896-015-0219-8

Ejemplares similares

Microcarrier Culture for Efficient Expansion and Osteogenic Differentiation of Human Fetal Mesenchymal Stem Cells
por: Goh, Tony Kwang-Poh, et al.
Publicado: (2013)

Critical attributes of human early mesenchymal stromal cell-laden microcarrier constructs for improved chondrogenic differentiation
por: Lin, Youshan Melissa, et al.
Publicado: (2017)

Improved Human Pluripotent Stem Cell Attachment and Spreading on Xeno-Free Laminin-521-Coated Microcarriers Results in Efficient Growth in Agitated Cultures
por: Lam, Alan Tin-Lun, et al.
Publicado: (2015)

An allied reprogramming, selection, expansion and differentiation platform for creating hiPSC on microcarriers
por: Lam, Alan Tin Lun, et al.
Publicado: (2022)

Conjoint propagation and differentiation of human embryonic stem cells to cardiomyocytes in a defined microcarrier spinner culture
por: Lam, Alan Tin-Lun, et al.
Publicado: (2014)

Selection of human induced pluripotent stem cells lines optimization of cardiomyocytes differentiation in an integrated suspension microcarrier bioreactor
por: Laco, Filip, et al.
Publicado: (2020)

Efficient expansion and delayed senescence of hUC-MSCs by microcarrier–bioreactor system
por: Wang, Xia, et al.
Publicado: (2023)

A controllable gelatin-based microcarriers fabrication system for the whole procedures of MSCs amplification and tissue engineering
por: Wang, Zixian, et al.
Publicado: (2023)

Shaped 3D microcarriers for adherent cell culture and analysis
por: Wu, Chueh-Yu, et al.
Publicado: (2018)

Manipulation of miRNA activity accelerates osteogenic differentiation of hMSCs in engineered 3D scaffolds
por: Mariner, Peter D, et al.
Publicado: (2012)

Long Term Expansion of Bone Marrow-Derived hMSCs on Novel Synthetic Microcarriers in Xeno-Free, Defined Conditions
por: Hervy, Martial, et al.
Publicado: (2014)

Proliferation and Osteogenic Differentiation of hMSCs on Biomineralized Collagen
por: de Melo Pereira, Daniel, et al.
Publicado: (2020)

Xeno-Free In Vitro Cultivation and Osteogenic Differentiation of hAD-MSCs on Resorbable 3D Printed RESOMER(®)
por: Kirsch, Marline, et al.
Publicado: (2020)

Expansion, harvest and cryopreservation of human mesenchymal stem cells in a serum‐free microcarrier process
por: Heathman, Thomas R. J., et al.
Publicado: (2015)

The response of human macrophages to 3D printed titanium antibacterial implants does not affect the osteogenic differentiation of hMSCs
por: Garmendia Urdalleta, Amaia, et al.
Publicado: (2023)

Dexamethasone-Activated MSCs Release MVs for Stimulating Osteogenic Response
por: Zhao, Mingyan, et al.
Publicado: (2018)

Macrophage type modulates osteogenic differentiation of adipose tissue MSCs
por: Zhang, Yang, et al.
Publicado: (2017)

(18)F- based Quantification of the Osteogenic Potential of hMSCs
por: Grossner, Tobias, et al.
Publicado: (2020)

Regulatory mechanisms of GCN5 in osteogenic differentiation of MSCs in periodontitis
por: Lu, Wei, et al.
Publicado: (2023)

Influence of operating parameters of a settling-based perfusion process on expansion of VERO cells attached on microcarriers
por: El Wajgali, Amal, et al.
Publicado: (2011)

Static and dynamic 3D culture of neural precursor cells on macroporous cryogel microcarriers
por: Newland, Ben, et al.
Publicado: (2020)

YAP as a key regulator of adipo-osteogenic differentiation in human MSCs
por: Lorthongpanich, Chanchao, et al.
Publicado: (2019)

The Myokine Irisin Promotes Osteogenic Differentiation of Dental Bud-Derived MSCs
por: Posa, Francesca, et al.
Publicado: (2021)

The Effects of Macrophage Phenotype on Osteogenic Differentiation of MSCs in the Presence of Polyethylene Particles
por: Gao, Qi, et al.
Publicado: (2021)

Self-assembled microtissues loaded with osteogenic MSCs for in vivo bone regeneration
por: Li, Hui, et al.
Publicado: (2022)

Stable Reference Genes for qPCR Analysis in BM-MSCs Undergoing Osteogenic Differentiation within 3D Hyaluronan-Based Hydrogels
por: Hasler, Johannes, et al.
Publicado: (2020)

Titanium phosphate glass microcarriers induce enhanced osteogenic cell proliferation and human mesenchymal stem cell protein expression
por: Lakhkar, Nilay J, et al.
Publicado: (2015)

The Effects of High Glucose on Adipogenic and Osteogenic Differentiation of Gestational Tissue-Derived MSCs
por: Hankamolsiri, Weerawan, et al.
Publicado: (2016)

Engineering microdent structures of bone implant surfaces to enhance osteogenic activity in MSCs
por: Li, Sophia, et al.
Publicado: (2016)

AFF1 and AFF4 differentially regulate the osteogenic differentiation of human MSCs
por: Zhou, Chen-chen, et al.
Publicado: (2017)

Is There a Noninvasive Source of MSCs Isolated with GMP Methods with Better Osteogenic Potential?
por: Pinheiro, Carla C. G., et al.
Publicado: (2019)

Integrating physicomechanical and biological strategies for BTE: biomaterials-induced osteogenic differentiation of MSCs
por: Shi, Huixin, et al.
Publicado: (2023)

Attachment of Mycoplasma pneumoniae to tracheal monolayer outgrowths.
por: Gabridge, M. G.
Publicado: (1983)

Early Osteogenic Marker Expression in hMSCs Cultured onto Acid Etching-Derived Micro- and Nanotopography 3D-Printed Titanium Surfaces
por: Bloise, Nora, et al.
Publicado: (2022)

Microcarriers for Upscaling Cultured Meat Production
por: Bodiou, Vincent, et al.
Publicado: (2020)

Polysaccharides as Stabilizers for Polymeric Microcarriers Fabrication
por: Demina, Tatiana S., et al.
Publicado: (2021)

Dnmt3a-Mediated DNA Methylation Changes Regulate Osteogenic Differentiation of hMSCs Cultivated in the 3D Scaffolds under Oxidative Stress
por: Li, Liangping, et al.
Publicado: (2019)

A Lox/CHOP‐10 crosstalk governs osteogenic and adipogenic cell fate by MSCs
por: Jiang, Wen‐yan, et al.
Publicado: (2018)

Low dose effect of bisphosphonates on hMSCs osteogenic response to titanium surface in vitro
por: Alqhtani, N.R., et al.
Publicado: (2017)

Bidirectional regulation of osteogenic differentiation by the FOXO subfamily of Forkhead transcription factors in mammalian MSCs
por: Chen, Duanjing, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_7o5o2miebc35e1aqdbnu5j751e