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Functional imaging for radiotherapy treatment planning: current status and future directions—a review
In recent years, radiotherapy (RT) has been subject to a number of technological innovations. Today, RT is extremely flexible, allowing irradiation of tumours with high doses, whilst also sparing normal tissues from doses. To make use of these additional degrees of freedom, integration of functional...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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The British Institute of Radiology.
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4628531/ https://www.ncbi.nlm.nih.gov/pubmed/25827209 http://dx.doi.org/10.1259/bjr.20150056 |
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author | Thorwarth, D |
author_facet | Thorwarth, D |
author_sort | Thorwarth, D |
collection | PubMed |
description | In recent years, radiotherapy (RT) has been subject to a number of technological innovations. Today, RT is extremely flexible, allowing irradiation of tumours with high doses, whilst also sparing normal tissues from doses. To make use of these additional degrees of freedom, integration of functional image information may play a key role (i) for better staging and tumour detection, (ii) for more accurate RT target volume delineation, (iii) to assess functional information about biological characteristics and individual radiation resistance and (iv) to apply personalized dose prescriptions. In this article, we discuss the current status and future directions of different clinically available functional imaging modalities; CT, MRI, positron emission tomography (PET) as well as the hybrid imaging techniques PET/CT and PET/MRI and their potential for individualized RT. |
format | Online Article Text |
id | pubmed-4628531 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | The British Institute of Radiology. |
record_format | MEDLINE/PubMed |
spelling | pubmed-46285312016-07-01 Functional imaging for radiotherapy treatment planning: current status and future directions—a review Thorwarth, D Br J Radiol Advances in Radiotherapy Special Feature In recent years, radiotherapy (RT) has been subject to a number of technological innovations. Today, RT is extremely flexible, allowing irradiation of tumours with high doses, whilst also sparing normal tissues from doses. To make use of these additional degrees of freedom, integration of functional image information may play a key role (i) for better staging and tumour detection, (ii) for more accurate RT target volume delineation, (iii) to assess functional information about biological characteristics and individual radiation resistance and (iv) to apply personalized dose prescriptions. In this article, we discuss the current status and future directions of different clinically available functional imaging modalities; CT, MRI, positron emission tomography (PET) as well as the hybrid imaging techniques PET/CT and PET/MRI and their potential for individualized RT. The British Institute of Radiology. 2015-07 2015-05-05 /pmc/articles/PMC4628531/ /pubmed/25827209 http://dx.doi.org/10.1259/bjr.20150056 Text en © 2015 The Authors. Published by the British Institute of Radiology This is an Open Access article distributed under the terms of the Creative Commons Attribution–NonCommercial 4.0 Unported License http://creativecommons.org/licenses/by-nc/4.0/, which permits unrestricted non-commercial reuse, provided the original author and source are credited. |
spellingShingle | Advances in Radiotherapy Special Feature Thorwarth, D Functional imaging for radiotherapy treatment planning: current status and future directions—a review |
title | Functional imaging for radiotherapy treatment planning: current status and future directions—a review |
title_full | Functional imaging for radiotherapy treatment planning: current status and future directions—a review |
title_fullStr | Functional imaging for radiotherapy treatment planning: current status and future directions—a review |
title_full_unstemmed | Functional imaging for radiotherapy treatment planning: current status and future directions—a review |
title_short | Functional imaging for radiotherapy treatment planning: current status and future directions—a review |
title_sort | functional imaging for radiotherapy treatment planning: current status and future directions—a review |
topic | Advances in Radiotherapy Special Feature |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4628531/ https://www.ncbi.nlm.nih.gov/pubmed/25827209 http://dx.doi.org/10.1259/bjr.20150056 |
work_keys_str_mv | AT thorwarthd functionalimagingforradiotherapytreatmentplanningcurrentstatusandfuturedirectionsareview |