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Radiotherapy for non-malignant disorders: state of the art and update of the evidence-based practice guidelines
Every year in Germany about 50,000 patients are referred and treated by radiotherapy (RT) for “non-malignant disorders”. This highly successful treatment is applied only for specific indications such as preservation or recovery of the quality of life by means of pain reduction or resolution and/or a...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The British Institute of Radiology.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4628533/ https://www.ncbi.nlm.nih.gov/pubmed/25955230 http://dx.doi.org/10.1259/bjr.20150080 |
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author | Seegenschmiedt, M H Micke, O Muecke, R |
author_facet | Seegenschmiedt, M H Micke, O Muecke, R |
author_sort | Seegenschmiedt, M H |
collection | PubMed |
description | Every year in Germany about 50,000 patients are referred and treated by radiotherapy (RT) for “non-malignant disorders”. This highly successful treatment is applied only for specific indications such as preservation or recovery of the quality of life by means of pain reduction or resolution and/or an improvement of formerly impaired physical body function owing to specific disease-related symptoms. Since 1995, German radiation oncologists have treated non-malignant disorders according to national consensus guidelines; these guidelines were updated and further developed over 3 years by implementation of a systematic consensus process to achieve national upgraded and accepted S2e clinical practice guidelines. Throughout this process, international standards of evaluation were implemented. This review summarizes most of the generally accepted indications for the application of RT for non-malignant diseases and presents the special treatment concepts. The following disease groups are addressed: painful degenerative skeletal disorders, hyperproliferative disorders and symptomatic functional disorders. These state of the art guidelines may serve as a platform for daily clinical work; they provide a new starting point for quality assessment, future clinical research, including the design of prospective clinical trials, and outcome research in the underrepresented and less appreciated field of RT for non-malignant disorders. |
format | Online Article Text |
id | pubmed-4628533 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | The British Institute of Radiology. |
record_format | MEDLINE/PubMed |
spelling | pubmed-46285332016-07-01 Radiotherapy for non-malignant disorders: state of the art and update of the evidence-based practice guidelines Seegenschmiedt, M H Micke, O Muecke, R Br J Radiol Advances in Radiotherapy Special Feature Every year in Germany about 50,000 patients are referred and treated by radiotherapy (RT) for “non-malignant disorders”. This highly successful treatment is applied only for specific indications such as preservation or recovery of the quality of life by means of pain reduction or resolution and/or an improvement of formerly impaired physical body function owing to specific disease-related symptoms. Since 1995, German radiation oncologists have treated non-malignant disorders according to national consensus guidelines; these guidelines were updated and further developed over 3 years by implementation of a systematic consensus process to achieve national upgraded and accepted S2e clinical practice guidelines. Throughout this process, international standards of evaluation were implemented. This review summarizes most of the generally accepted indications for the application of RT for non-malignant diseases and presents the special treatment concepts. The following disease groups are addressed: painful degenerative skeletal disorders, hyperproliferative disorders and symptomatic functional disorders. These state of the art guidelines may serve as a platform for daily clinical work; they provide a new starting point for quality assessment, future clinical research, including the design of prospective clinical trials, and outcome research in the underrepresented and less appreciated field of RT for non-malignant disorders. The British Institute of Radiology. 2015-07 2015-06-12 /pmc/articles/PMC4628533/ /pubmed/25955230 http://dx.doi.org/10.1259/bjr.20150080 Text en © 2015 The Authors. Published by the British Institute of Radiology This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 Unported License http://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Advances in Radiotherapy Special Feature Seegenschmiedt, M H Micke, O Muecke, R Radiotherapy for non-malignant disorders: state of the art and update of the evidence-based practice guidelines |
title | Radiotherapy for non-malignant disorders: state of the art and update of the evidence-based practice guidelines |
title_full | Radiotherapy for non-malignant disorders: state of the art and update of the evidence-based practice guidelines |
title_fullStr | Radiotherapy for non-malignant disorders: state of the art and update of the evidence-based practice guidelines |
title_full_unstemmed | Radiotherapy for non-malignant disorders: state of the art and update of the evidence-based practice guidelines |
title_short | Radiotherapy for non-malignant disorders: state of the art and update of the evidence-based practice guidelines |
title_sort | radiotherapy for non-malignant disorders: state of the art and update of the evidence-based practice guidelines |
topic | Advances in Radiotherapy Special Feature |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4628533/ https://www.ncbi.nlm.nih.gov/pubmed/25955230 http://dx.doi.org/10.1259/bjr.20150080 |
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