Is It Time to Beta Block the Septic Patient?

Beta blockers are some of the most studied drugs in the pharmacopoeia. They are already widely used in medicine for treating hypertension, chronic heart failure, tachyarrhythmias, and tremor. Whilst their use in the immediate perioperative patient has been questioned, the use of esmolol in the patie...

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Detalles Bibliográficos
Autores principales: Pemberton, Philip, Veenith, Tonny, Snelson, Catherine, Whitehouse, Tony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4628753/
https://www.ncbi.nlm.nih.gov/pubmed/26557668
http://dx.doi.org/10.1155/2015/424308
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author Pemberton, Philip
Veenith, Tonny
Snelson, Catherine
Whitehouse, Tony
author_facet Pemberton, Philip
Veenith, Tonny
Snelson, Catherine
Whitehouse, Tony
author_sort Pemberton, Philip
collection PubMed
description Beta blockers are some of the most studied drugs in the pharmacopoeia. They are already widely used in medicine for treating hypertension, chronic heart failure, tachyarrhythmias, and tremor. Whilst their use in the immediate perioperative patient has been questioned, the use of esmolol in the patients with established septic shock has been recently reported to have favourable outcomes. In this paper, we review the role of the adrenergic system in sepsis and the evidence for the use of beta stimulation and beta blockers from animal models to critically ill patients.
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spelling pubmed-46287532015-11-09 Is It Time to Beta Block the Septic Patient? Pemberton, Philip Veenith, Tonny Snelson, Catherine Whitehouse, Tony Biomed Res Int Review Article Beta blockers are some of the most studied drugs in the pharmacopoeia. They are already widely used in medicine for treating hypertension, chronic heart failure, tachyarrhythmias, and tremor. Whilst their use in the immediate perioperative patient has been questioned, the use of esmolol in the patients with established septic shock has been recently reported to have favourable outcomes. In this paper, we review the role of the adrenergic system in sepsis and the evidence for the use of beta stimulation and beta blockers from animal models to critically ill patients. Hindawi Publishing Corporation 2015 2015-10-18 /pmc/articles/PMC4628753/ /pubmed/26557668 http://dx.doi.org/10.1155/2015/424308 Text en Copyright © 2015 Philip Pemberton et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Pemberton, Philip
Veenith, Tonny
Snelson, Catherine
Whitehouse, Tony
Is It Time to Beta Block the Septic Patient?
title Is It Time to Beta Block the Septic Patient?
title_full Is It Time to Beta Block the Septic Patient?
title_fullStr Is It Time to Beta Block the Septic Patient?
title_full_unstemmed Is It Time to Beta Block the Septic Patient?
title_short Is It Time to Beta Block the Septic Patient?
title_sort is it time to beta block the septic patient?
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4628753/
https://www.ncbi.nlm.nih.gov/pubmed/26557668
http://dx.doi.org/10.1155/2015/424308
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