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The Association between Job Strain and Atrial Fibrillation: Results from the Swedish WOLF Study

Introduction. Atrial fibrillation (AF) is a common heart rhythm disorder. Several life-style factors have been identified as risk factors for AF, but less is known about the impact of work-related stress. This study aims to evaluate the association between work-related stress, defined as job strain,...

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Autores principales: Fransson, Eleonor I., Stadin, Magdalena, Nordin, Maria, Malm, Dan, Knutsson, Anders, Alfredsson, Lars, Westerholm, Peter J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4628762/
https://www.ncbi.nlm.nih.gov/pubmed/26557661
http://dx.doi.org/10.1155/2015/371905
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author Fransson, Eleonor I.
Stadin, Magdalena
Nordin, Maria
Malm, Dan
Knutsson, Anders
Alfredsson, Lars
Westerholm, Peter J. M.
author_facet Fransson, Eleonor I.
Stadin, Magdalena
Nordin, Maria
Malm, Dan
Knutsson, Anders
Alfredsson, Lars
Westerholm, Peter J. M.
author_sort Fransson, Eleonor I.
collection PubMed
description Introduction. Atrial fibrillation (AF) is a common heart rhythm disorder. Several life-style factors have been identified as risk factors for AF, but less is known about the impact of work-related stress. This study aims to evaluate the association between work-related stress, defined as job strain, and risk of AF. Methods. Data from the Swedish WOLF study was used, comprising 10,121 working men and women. Job strain was measured by the demand-control model. Information on incident AF was derived from national registers. Cox proportional hazard regression was used to estimate hazard ratios (HR) and 95% confidence intervals (CI) for the association between job strain and AF risk. Results. In total, 253 incident AF cases were identified during a total follow-up time of 132,387 person-years. Job strain was associated with AF risk in a time-dependent manner, with stronger association after 10.7 years of follow-up (HR 1.93, 95% CI 1.10–3.36 after 10.7 years, versus HR 1.11, 95% CI 0.67–1.83 before 10.7 years). The results pointed towards a dose-response relationship when taking accumulated exposure to job strain over time into account. Conclusion. This study provides support to the hypothesis that work-related stress defined as job strain is linked to an increased risk of AF.
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spelling pubmed-46287622015-11-09 The Association between Job Strain and Atrial Fibrillation: Results from the Swedish WOLF Study Fransson, Eleonor I. Stadin, Magdalena Nordin, Maria Malm, Dan Knutsson, Anders Alfredsson, Lars Westerholm, Peter J. M. Biomed Res Int Research Article Introduction. Atrial fibrillation (AF) is a common heart rhythm disorder. Several life-style factors have been identified as risk factors for AF, but less is known about the impact of work-related stress. This study aims to evaluate the association between work-related stress, defined as job strain, and risk of AF. Methods. Data from the Swedish WOLF study was used, comprising 10,121 working men and women. Job strain was measured by the demand-control model. Information on incident AF was derived from national registers. Cox proportional hazard regression was used to estimate hazard ratios (HR) and 95% confidence intervals (CI) for the association between job strain and AF risk. Results. In total, 253 incident AF cases were identified during a total follow-up time of 132,387 person-years. Job strain was associated with AF risk in a time-dependent manner, with stronger association after 10.7 years of follow-up (HR 1.93, 95% CI 1.10–3.36 after 10.7 years, versus HR 1.11, 95% CI 0.67–1.83 before 10.7 years). The results pointed towards a dose-response relationship when taking accumulated exposure to job strain over time into account. Conclusion. This study provides support to the hypothesis that work-related stress defined as job strain is linked to an increased risk of AF. Hindawi Publishing Corporation 2015 2015-10-18 /pmc/articles/PMC4628762/ /pubmed/26557661 http://dx.doi.org/10.1155/2015/371905 Text en Copyright © 2015 Eleonor I. Fransson et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Fransson, Eleonor I.
Stadin, Magdalena
Nordin, Maria
Malm, Dan
Knutsson, Anders
Alfredsson, Lars
Westerholm, Peter J. M.
The Association between Job Strain and Atrial Fibrillation: Results from the Swedish WOLF Study
title The Association between Job Strain and Atrial Fibrillation: Results from the Swedish WOLF Study
title_full The Association between Job Strain and Atrial Fibrillation: Results from the Swedish WOLF Study
title_fullStr The Association between Job Strain and Atrial Fibrillation: Results from the Swedish WOLF Study
title_full_unstemmed The Association between Job Strain and Atrial Fibrillation: Results from the Swedish WOLF Study
title_short The Association between Job Strain and Atrial Fibrillation: Results from the Swedish WOLF Study
title_sort association between job strain and atrial fibrillation: results from the swedish wolf study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4628762/
https://www.ncbi.nlm.nih.gov/pubmed/26557661
http://dx.doi.org/10.1155/2015/371905
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