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Complete or partial reduction of the Met receptor tyrosine kinase in distinct circuits differentially impacts mouse behavior

BACKGROUND: Our laboratory discovered that the gene encoding the receptor tyrosine kinase, MET, contributes to autism risk. Expression of MET is reduced in human postmortem temporal lobe in autism and Rett Syndrome. Subsequent studies revealed a role for MET in human and mouse functional and structu...

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Detalles Bibliográficos
Autores principales: Thompson, Barbara L., Levitt, Pat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4628780/
https://www.ncbi.nlm.nih.gov/pubmed/26523156
http://dx.doi.org/10.1186/s11689-015-9131-8

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