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A Clinical Picture of the Visual Outcome in Adamantiades-Behçet's Disease

Adamantiades-Behçet's disease is a multisystemic vasculitis with multiorgan involvement. Ocular disorders occur often in this syndrome typically in the form of a relapsing-remitting panuveitis and vasculitis and can lead to blindness as one of its most disabling complications if left untreated....

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Autores principales: Figus, Michele, Posarelli, Chiara, Albert, Timothy G., Talarico, Rosaria, Nardi, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4628956/
https://www.ncbi.nlm.nih.gov/pubmed/26558256
http://dx.doi.org/10.1155/2015/120519
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author Figus, Michele
Posarelli, Chiara
Albert, Timothy G.
Talarico, Rosaria
Nardi, Marco
author_facet Figus, Michele
Posarelli, Chiara
Albert, Timothy G.
Talarico, Rosaria
Nardi, Marco
author_sort Figus, Michele
collection PubMed
description Adamantiades-Behçet's disease is a multisystemic vasculitis with multiorgan involvement. Ocular disorders occur often in this syndrome typically in the form of a relapsing-remitting panuveitis and vasculitis and can lead to blindness as one of its most disabling complications if left untreated. There are known risk factors related with the worst visual prognosis, which require early and intensive treatment in order to obtain a rapid suppression of inflammation and to prevent future relapses. The management strategy to avoid vision loss and blindness currently involves the use of local and systemic drugs including steroids and immunosuppressive and biologic agents. This review aims to demonstrate how the introduction and the use of biologic agents improves the visual outcome of patients with Adamantiades-Behçet's disease.
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spelling pubmed-46289562015-11-10 A Clinical Picture of the Visual Outcome in Adamantiades-Behçet's Disease Figus, Michele Posarelli, Chiara Albert, Timothy G. Talarico, Rosaria Nardi, Marco Biomed Res Int Review Article Adamantiades-Behçet's disease is a multisystemic vasculitis with multiorgan involvement. Ocular disorders occur often in this syndrome typically in the form of a relapsing-remitting panuveitis and vasculitis and can lead to blindness as one of its most disabling complications if left untreated. There are known risk factors related with the worst visual prognosis, which require early and intensive treatment in order to obtain a rapid suppression of inflammation and to prevent future relapses. The management strategy to avoid vision loss and blindness currently involves the use of local and systemic drugs including steroids and immunosuppressive and biologic agents. This review aims to demonstrate how the introduction and the use of biologic agents improves the visual outcome of patients with Adamantiades-Behçet's disease. Hindawi Publishing Corporation 2015 2015-10-19 /pmc/articles/PMC4628956/ /pubmed/26558256 http://dx.doi.org/10.1155/2015/120519 Text en Copyright © 2015 Michele Figus et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Figus, Michele
Posarelli, Chiara
Albert, Timothy G.
Talarico, Rosaria
Nardi, Marco
A Clinical Picture of the Visual Outcome in Adamantiades-Behçet's Disease
title A Clinical Picture of the Visual Outcome in Adamantiades-Behçet's Disease
title_full A Clinical Picture of the Visual Outcome in Adamantiades-Behçet's Disease
title_fullStr A Clinical Picture of the Visual Outcome in Adamantiades-Behçet's Disease
title_full_unstemmed A Clinical Picture of the Visual Outcome in Adamantiades-Behçet's Disease
title_short A Clinical Picture of the Visual Outcome in Adamantiades-Behçet's Disease
title_sort clinical picture of the visual outcome in adamantiades-behçet's disease
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4628956/
https://www.ncbi.nlm.nih.gov/pubmed/26558256
http://dx.doi.org/10.1155/2015/120519
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