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A Clinical Picture of the Visual Outcome in Adamantiades-Behçet's Disease
Adamantiades-Behçet's disease is a multisystemic vasculitis with multiorgan involvement. Ocular disorders occur often in this syndrome typically in the form of a relapsing-remitting panuveitis and vasculitis and can lead to blindness as one of its most disabling complications if left untreated....
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4628956/ https://www.ncbi.nlm.nih.gov/pubmed/26558256 http://dx.doi.org/10.1155/2015/120519 |
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author | Figus, Michele Posarelli, Chiara Albert, Timothy G. Talarico, Rosaria Nardi, Marco |
author_facet | Figus, Michele Posarelli, Chiara Albert, Timothy G. Talarico, Rosaria Nardi, Marco |
author_sort | Figus, Michele |
collection | PubMed |
description | Adamantiades-Behçet's disease is a multisystemic vasculitis with multiorgan involvement. Ocular disorders occur often in this syndrome typically in the form of a relapsing-remitting panuveitis and vasculitis and can lead to blindness as one of its most disabling complications if left untreated. There are known risk factors related with the worst visual prognosis, which require early and intensive treatment in order to obtain a rapid suppression of inflammation and to prevent future relapses. The management strategy to avoid vision loss and blindness currently involves the use of local and systemic drugs including steroids and immunosuppressive and biologic agents. This review aims to demonstrate how the introduction and the use of biologic agents improves the visual outcome of patients with Adamantiades-Behçet's disease. |
format | Online Article Text |
id | pubmed-4628956 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-46289562015-11-10 A Clinical Picture of the Visual Outcome in Adamantiades-Behçet's Disease Figus, Michele Posarelli, Chiara Albert, Timothy G. Talarico, Rosaria Nardi, Marco Biomed Res Int Review Article Adamantiades-Behçet's disease is a multisystemic vasculitis with multiorgan involvement. Ocular disorders occur often in this syndrome typically in the form of a relapsing-remitting panuveitis and vasculitis and can lead to blindness as one of its most disabling complications if left untreated. There are known risk factors related with the worst visual prognosis, which require early and intensive treatment in order to obtain a rapid suppression of inflammation and to prevent future relapses. The management strategy to avoid vision loss and blindness currently involves the use of local and systemic drugs including steroids and immunosuppressive and biologic agents. This review aims to demonstrate how the introduction and the use of biologic agents improves the visual outcome of patients with Adamantiades-Behçet's disease. Hindawi Publishing Corporation 2015 2015-10-19 /pmc/articles/PMC4628956/ /pubmed/26558256 http://dx.doi.org/10.1155/2015/120519 Text en Copyright © 2015 Michele Figus et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Figus, Michele Posarelli, Chiara Albert, Timothy G. Talarico, Rosaria Nardi, Marco A Clinical Picture of the Visual Outcome in Adamantiades-Behçet's Disease |
title | A Clinical Picture of the Visual Outcome in Adamantiades-Behçet's Disease |
title_full | A Clinical Picture of the Visual Outcome in Adamantiades-Behçet's Disease |
title_fullStr | A Clinical Picture of the Visual Outcome in Adamantiades-Behçet's Disease |
title_full_unstemmed | A Clinical Picture of the Visual Outcome in Adamantiades-Behçet's Disease |
title_short | A Clinical Picture of the Visual Outcome in Adamantiades-Behçet's Disease |
title_sort | clinical picture of the visual outcome in adamantiades-behçet's disease |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4628956/ https://www.ncbi.nlm.nih.gov/pubmed/26558256 http://dx.doi.org/10.1155/2015/120519 |
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