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PD173074, a selective FGFR inhibitor, reverses MRP7 (ABCC10)-mediated MDR
Multidrug resistance protein 7 (MRP7, ABCC10) is a recently identified member of the ATP-binding cassette (ABC) transporter family, which adequately confers resistance to a diverse group of antineoplastic agents, including taxanes, vinca alkaloids and nucleoside analogs among others. Clinical studie...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4629066/ https://www.ncbi.nlm.nih.gov/pubmed/26579384 http://dx.doi.org/10.1016/j.apsb.2014.02.003 |