Cortical folding and the potential for prognostic neuroimaging in schizophrenia

In 41 patients with schizophrenia, we used neuroanatomical information derived from structural imaging to identify patients with more severe illness, characterised by high symptom burden, low processing speed, high degree of illness persistence and lower social and occupational functional capacity....

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Detalles Bibliográficos
Autores principales: Guo, Shuixia, Iwabuchi, Sarina, Balain, Vijender, Feng, Jianfeng, Liddle, Peter, Palaniyappan, Lena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal College of Psychiatrists 2015
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4629075/
https://www.ncbi.nlm.nih.gov/pubmed/26206860
http://dx.doi.org/10.1192/bjp.bp.114.155796
Descripción
Sumario:In 41 patients with schizophrenia, we used neuroanatomical information derived from structural imaging to identify patients with more severe illness, characterised by high symptom burden, low processing speed, high degree of illness persistence and lower social and occupational functional capacity. Cortical folding, but not thickness or volume, showed a high discriminatory ability in correctly identifying patients with more severe illness.

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