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Initial amplification of the HPV18 genome proceeds via two distinct replication mechanisms

Determining the mechanism of HPV18 replication is paramount for identifying possible drug targets against HPV infection. We used two-dimensional and three-dimensional gel electrophoresis techniques to identify replication intermediates arising during the initial amplification of HPV18 episomal genom...

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Detalles Bibliográficos
Autores principales: Orav, Marit, Geimanen, Jelizaveta, Sepp, Eva-Maria, Henno, Liisi, Ustav, Ene, Ustav, Mart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4629122/
https://www.ncbi.nlm.nih.gov/pubmed/26522968
http://dx.doi.org/10.1038/srep15952