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Human induced pluripotent stem cell‐derived versus adult cardiomyocytes: an in silico electrophysiological study on effects of ionic current block
BACKGROUND AND PURPOSE: Two new technologies are likely to revolutionize cardiac safety and drug development: in vitro experiments on human‐induced pluripotent stem cell‐derived cardiomyocytes (hiPSC‐CMs) and in silico human adult ventricular cardiomyocyte (hAdultV‐CM) models. Their combination was...
Autores principales: | Paci, M, Hyttinen, J, Rodriguez, B, Severi, S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4629192/ https://www.ncbi.nlm.nih.gov/pubmed/26276951 http://dx.doi.org/10.1111/bph.13282 |
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