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Generation of hypoxanthine phosphoribosyltransferase gene knockout rabbits by homologous recombination and gene trapping through somatic cell nuclear transfer

The rabbit is a common animal model that has been employed in studies on various human disorders, and the generation of genetically modified rabbit lines is highly desirable. Female rabbits have been successfully cloned from cumulus cells, and the somatic cell nuclear transfer (SCNT) technology is w...

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Detalles Bibliográficos
Autores principales:	Yin, Mingru, Jiang, Weihua, Fang, Zhenfu, Kong, Pengcheng, Xing, Fengying, Li, Yao, Chen, Xuejin, Li, Shangang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4629196/ https://www.ncbi.nlm.nih.gov/pubmed/26522387 http://dx.doi.org/10.1038/srep16023

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