Development of a new ferulic acid certified reference material for use in clinical chemistry and pharmaceutical analysis

This study compares the results of three certified methods, namely differential scanning calorimetry (DSC), the mass balance (MB) method and coulometric titrimetry (CT), in the purity assessment of ferulic acid certified reference material (CRM). Purity and expanded uncertainty as determined by the...

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Detalles Bibliográficos
Autores principales: Yang, Dezhi, Wang, Fengfeng, Zhang, Li, Gong, Ningbo, Lv, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4629261/
https://www.ncbi.nlm.nih.gov/pubmed/26579451
http://dx.doi.org/10.1016/j.apsb.2015.03.009
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author Yang, Dezhi
Wang, Fengfeng
Zhang, Li
Gong, Ningbo
Lv, Yang
author_facet Yang, Dezhi
Wang, Fengfeng
Zhang, Li
Gong, Ningbo
Lv, Yang
author_sort Yang, Dezhi
collection PubMed
description This study compares the results of three certified methods, namely differential scanning calorimetry (DSC), the mass balance (MB) method and coulometric titrimetry (CT), in the purity assessment of ferulic acid certified reference material (CRM). Purity and expanded uncertainty as determined by the three methods were respectively 99.81%, 0.16%; 99.79%, 0.16%; and 99.81%, 0.26% with, in all cases, a coverage factor (k) of 2 (P=95%). The purity results are consistent indicating that the combination of DSC, the MB method and CT provides a confident assessment of the purity of suitable CRMs like ferulic acid.
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spelling pubmed-46292612015-11-17 Development of a new ferulic acid certified reference material for use in clinical chemistry and pharmaceutical analysis Yang, Dezhi Wang, Fengfeng Zhang, Li Gong, Ningbo Lv, Yang Acta Pharm Sin B Original Article This study compares the results of three certified methods, namely differential scanning calorimetry (DSC), the mass balance (MB) method and coulometric titrimetry (CT), in the purity assessment of ferulic acid certified reference material (CRM). Purity and expanded uncertainty as determined by the three methods were respectively 99.81%, 0.16%; 99.79%, 0.16%; and 99.81%, 0.26% with, in all cases, a coverage factor (k) of 2 (P=95%). The purity results are consistent indicating that the combination of DSC, the MB method and CT provides a confident assessment of the purity of suitable CRMs like ferulic acid. Elsevier 2015-05 2015-04-08 /pmc/articles/PMC4629261/ /pubmed/26579451 http://dx.doi.org/10.1016/j.apsb.2015.03.009 Text en © 2015 Chinese Pharmaceutical Association and Institute of Materia Medica, Chinese Academy of Medical Sciences. Production and hosting by Elsevier B.V. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Original Article
Yang, Dezhi
Wang, Fengfeng
Zhang, Li
Gong, Ningbo
Lv, Yang
Development of a new ferulic acid certified reference material for use in clinical chemistry and pharmaceutical analysis
title Development of a new ferulic acid certified reference material for use in clinical chemistry and pharmaceutical analysis
title_full Development of a new ferulic acid certified reference material for use in clinical chemistry and pharmaceutical analysis
title_fullStr Development of a new ferulic acid certified reference material for use in clinical chemistry and pharmaceutical analysis
title_full_unstemmed Development of a new ferulic acid certified reference material for use in clinical chemistry and pharmaceutical analysis
title_short Development of a new ferulic acid certified reference material for use in clinical chemistry and pharmaceutical analysis
title_sort development of a new ferulic acid certified reference material for use in clinical chemistry and pharmaceutical analysis
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4629261/
https://www.ncbi.nlm.nih.gov/pubmed/26579451
http://dx.doi.org/10.1016/j.apsb.2015.03.009
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