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Pharmacokinetic analysis and tissue distribution of Vam3 in the rat by a validated LC-MS/MS method
Vam3 is a potential pharmacologically active ingredient isolated from Vitis amurensis Rupr. A rapid, simple and sensitive method to determine Vam3 levels in rat plasma and tissue was developed based on LC-MS/MS. Vam3 and an internal standard (IS) were chromatographed on a C18 short column with aceto...
Autores principales: | Zhang, Ruixia, Mao, Ping, Zhang, Tingting, Ma, Chen, Jin, Bo, Li, Tong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4629264/ https://www.ncbi.nlm.nih.gov/pubmed/26579454 http://dx.doi.org/10.1016/j.apsb.2015.03.011 |
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