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Synthesis and antiviral activity of a series of novel N-phenylbenzamide and N-phenylacetophenone compounds as anti-HCV and anti-EV71 agents
A series of novel N-phenylbenzamide and N-phenylacetophenone compounds were synthesized and evaluated for their antiviral activity against HCV and EV71 (strain SZ-98). The biological results showed that three compounds (23, 25 and 41) exhibited considerable anti-HCV activity (IC(50)=0.57–7.12 μmol/L...
Autores principales: | Jiang, Zhi, Wang, Huiqiang, Li, Yanping, Peng, Zonggen, Li, Yuhuan, Li, Zhuorong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4629265/ https://www.ncbi.nlm.nih.gov/pubmed/26579447 http://dx.doi.org/10.1016/j.apsb.2015.03.013 |
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