Synthesis, potential anticonvulsant and antidepressant effects of 2-(5-methyl-2,3-dioxoindolin-1-yl)acetamide derivatives

A new series of 2-(5-methyl-2,3-dioxoindolin-1-yl)acetamide derivatives were synthesized and evaluated for their anticonvulsive activity in a pentylenetetrazole (PTZ)-evoked convulsion model and antidepressant activity in the forced swimming test (FST) model. Eleven synthesized compounds were found...

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Detalles Bibliográficos
Autores principales: Zhen, Xinghua, Peng, Zhou, Zhao, Shuilian, Han, Yan, Jin, Qinghao, Guan, Liping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4629268/
https://www.ncbi.nlm.nih.gov/pubmed/26579465
http://dx.doi.org/10.1016/j.apsb.2015.01.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4629268/
https://www.ncbi.nlm.nih.gov/pubmed/26579465
http://dx.doi.org/10.1016/j.apsb.2015.01.008

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