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Methotrexate as an oral corticosteroid-sparing agent in severe asthma: the emergence of a responder asthma endotype
BACKGROUND: Sustained use of oral corticosteroids is associated with significant side effects. It is therefore of interest to find a corticosteroid-sparing agent. In two meta-analyses, methotrexate resulted in a rather small reduction in the oral corticosteroid maintenance dose. We have used methotr...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Co-Action Publishing
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4629721/ https://www.ncbi.nlm.nih.gov/pubmed/26557239 http://dx.doi.org/10.3402/ecrj.v1.25037 |