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The kinetochore encodes a mechanical switch to disrupt spindle assembly checkpoint signaling

The Spindle Assembly Checkpoint (SAC) is a unique signaling mechanism that responds to the state of attachment of the kinetochore to spindle microtubules. SAC signaling is activated by unattached kinetochores, and it is silenced after these kinetochores form end-on microtubule attachments. Although...

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Detalles Bibliográficos
Autores principales:	Aravamudhan, Pavithra, Goldfarb, Alan A., Joglekar, Ajit P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630029/ https://www.ncbi.nlm.nih.gov/pubmed/26053220 http://dx.doi.org/10.1038/ncb3179

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