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Does Sedation Affect Examination of Esophagogastric Junction during Upper Endoscopy?
PURPOSE: During sedated esophagogastroduodenoscopy (EGD), patients may not be able to perform inspiration, which is necessary to examine the esophagogastric junction. Therefore sedation may affect diagnosis of gastroesophageal reflux-related findings. The aim of our study was to investigate the effe...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Yonsei University College of Medicine
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630044/ https://www.ncbi.nlm.nih.gov/pubmed/26446638 http://dx.doi.org/10.3349/ymj.2015.56.6.1566 |
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author | Lee, Hyun Jik Kim, Bun Kim, Dong Wook Park, Jun Chul Shin, Sung Kwan Lee, Yong Chan Lee, Sang Kil |
author_facet | Lee, Hyun Jik Kim, Bun Kim, Dong Wook Park, Jun Chul Shin, Sung Kwan Lee, Yong Chan Lee, Sang Kil |
author_sort | Lee, Hyun Jik |
collection | PubMed |
description | PURPOSE: During sedated esophagogastroduodenoscopy (EGD), patients may not be able to perform inspiration, which is necessary to examine the esophagogastric junction. Therefore sedation may affect diagnosis of gastroesophageal reflux-related findings. The aim of our study was to investigate the effect of sedation on diagnosis of gastroesophageal reflux-related findings during EGD. MATERIALS AND METHODS: This retrospective study evaluated 28914 patients older than 20 years who underwent EGD at our institution between January 2011 and December 2011. Ultimately, 1546 patients indicated for EGD for health check-up and symptom evaluation were included. RESULTS: There were 18546 patients who had diagnostic EGD: 10471 patients (56%) by non-sedated EGD and 8075 patients (43%) by sedated EGD. After statistical adjustment for age, sex, and body mass index, minimal change esophagitis, and hiatal hernia were significantly less frequently observed in the sedated EGD group [odds ratio (OR), 0.651; 95% confidence interval (CI), 0.586 to 0.722 and OR, 0.699; 95% CI, 0.564 to 0.866]. Nevertheless, there was no significant difference in other findings at the gastroesophageal junction, such as reflux esophagitis with Los Angeles classification A, B, C, and D or Barrett's esophagus, between the two groups. Similarly, there were no differences in early gastric cancer, advanced gastric cancer, and gastric ulcer occurrence. CONCLUSION: Sedation can impede the detection of minimal change esophagitis and hiatal hernia, but does not influence detection of reflux esophagitis of definite severity and Barrett's esophagus. |
format | Online Article Text |
id | pubmed-4630044 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Yonsei University College of Medicine |
record_format | MEDLINE/PubMed |
spelling | pubmed-46300442015-11-04 Does Sedation Affect Examination of Esophagogastric Junction during Upper Endoscopy? Lee, Hyun Jik Kim, Bun Kim, Dong Wook Park, Jun Chul Shin, Sung Kwan Lee, Yong Chan Lee, Sang Kil Yonsei Med J Original Article PURPOSE: During sedated esophagogastroduodenoscopy (EGD), patients may not be able to perform inspiration, which is necessary to examine the esophagogastric junction. Therefore sedation may affect diagnosis of gastroesophageal reflux-related findings. The aim of our study was to investigate the effect of sedation on diagnosis of gastroesophageal reflux-related findings during EGD. MATERIALS AND METHODS: This retrospective study evaluated 28914 patients older than 20 years who underwent EGD at our institution between January 2011 and December 2011. Ultimately, 1546 patients indicated for EGD for health check-up and symptom evaluation were included. RESULTS: There were 18546 patients who had diagnostic EGD: 10471 patients (56%) by non-sedated EGD and 8075 patients (43%) by sedated EGD. After statistical adjustment for age, sex, and body mass index, minimal change esophagitis, and hiatal hernia were significantly less frequently observed in the sedated EGD group [odds ratio (OR), 0.651; 95% confidence interval (CI), 0.586 to 0.722 and OR, 0.699; 95% CI, 0.564 to 0.866]. Nevertheless, there was no significant difference in other findings at the gastroesophageal junction, such as reflux esophagitis with Los Angeles classification A, B, C, and D or Barrett's esophagus, between the two groups. Similarly, there were no differences in early gastric cancer, advanced gastric cancer, and gastric ulcer occurrence. CONCLUSION: Sedation can impede the detection of minimal change esophagitis and hiatal hernia, but does not influence detection of reflux esophagitis of definite severity and Barrett's esophagus. Yonsei University College of Medicine 2015-11-01 2015-09-25 /pmc/articles/PMC4630044/ /pubmed/26446638 http://dx.doi.org/10.3349/ymj.2015.56.6.1566 Text en © Copyright: Yonsei University College of Medicine 2015 http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Lee, Hyun Jik Kim, Bun Kim, Dong Wook Park, Jun Chul Shin, Sung Kwan Lee, Yong Chan Lee, Sang Kil Does Sedation Affect Examination of Esophagogastric Junction during Upper Endoscopy? |
title | Does Sedation Affect Examination of Esophagogastric Junction during Upper Endoscopy? |
title_full | Does Sedation Affect Examination of Esophagogastric Junction during Upper Endoscopy? |
title_fullStr | Does Sedation Affect Examination of Esophagogastric Junction during Upper Endoscopy? |
title_full_unstemmed | Does Sedation Affect Examination of Esophagogastric Junction during Upper Endoscopy? |
title_short | Does Sedation Affect Examination of Esophagogastric Junction during Upper Endoscopy? |
title_sort | does sedation affect examination of esophagogastric junction during upper endoscopy? |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630044/ https://www.ncbi.nlm.nih.gov/pubmed/26446638 http://dx.doi.org/10.3349/ymj.2015.56.6.1566 |
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