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Successful Treatment of Infectious Scleritis by Pseudomonas aeruginosa with Autologous Perichondrium Graft of Conchal Cartilage

Infectious scleritis by Pseudomonas aeruginosa is a well-known vision-threatening disease. In particular, scleral trauma following pterygium surgery may increase the risk of sclera inflammation. Surgical debridement and repair is necessary in patients who do not respond to medical treatments, such a...

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Autores principales: Yoo, Woong Sun, Kim, Che Ron, Kim, Byung Jae, Ahn, Seong Ki, Seo, Seong Wook, Yoo, Ji Myong, Kim, Seong Jae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Yonsei University College of Medicine 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630068/
https://www.ncbi.nlm.nih.gov/pubmed/26446662
http://dx.doi.org/10.3349/ymj.2015.56.6.1738
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author Yoo, Woong Sun
Kim, Che Ron
Kim, Byung Jae
Ahn, Seong Ki
Seo, Seong Wook
Yoo, Ji Myong
Kim, Seong Jae
author_facet Yoo, Woong Sun
Kim, Che Ron
Kim, Byung Jae
Ahn, Seong Ki
Seo, Seong Wook
Yoo, Ji Myong
Kim, Seong Jae
author_sort Yoo, Woong Sun
collection PubMed
description Infectious scleritis by Pseudomonas aeruginosa is a well-known vision-threatening disease. In particular, scleral trauma following pterygium surgery may increase the risk of sclera inflammation. Surgical debridement and repair is necessary in patients who do not respond to medical treatments, such as topical and intravenous antibiotics. We reports herein the effectiveness of an autologous perichondrium conchal cartilage graft for infectious scleritis caused by Pseudomonas aeruginosa. This procedure was performed on four eyes of four patients with infectious scleritis who had previously undergone pterygium surgery at Gyeongsang National University Hospital (GNUH), Jinju, Korea from December 2011 to May 2012. Pseudomonas aeruginosa was identified in cultures of necrotic scleral lesion before surgery. The conchal cartilage perichondrium graft was transplanted, and a conjunctival flap was created on the scleral lesion. The autologous perichondrium conchal cartilage graft was successful and visual outcome was stable in all patients, with no reports of graft failure or infection recurrence. In conclusion, autologous perichondrium conchal cartilage graft may be effective in surgical management of Pseudomonal infectious scleritis when non-surgical medical treatment is ineffective. Further studies in larger, diverse populations are warranted to establish the effectiveness of the procedure.
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spelling pubmed-46300682015-11-04 Successful Treatment of Infectious Scleritis by Pseudomonas aeruginosa with Autologous Perichondrium Graft of Conchal Cartilage Yoo, Woong Sun Kim, Che Ron Kim, Byung Jae Ahn, Seong Ki Seo, Seong Wook Yoo, Ji Myong Kim, Seong Jae Yonsei Med J Case Report Infectious scleritis by Pseudomonas aeruginosa is a well-known vision-threatening disease. In particular, scleral trauma following pterygium surgery may increase the risk of sclera inflammation. Surgical debridement and repair is necessary in patients who do not respond to medical treatments, such as topical and intravenous antibiotics. We reports herein the effectiveness of an autologous perichondrium conchal cartilage graft for infectious scleritis caused by Pseudomonas aeruginosa. This procedure was performed on four eyes of four patients with infectious scleritis who had previously undergone pterygium surgery at Gyeongsang National University Hospital (GNUH), Jinju, Korea from December 2011 to May 2012. Pseudomonas aeruginosa was identified in cultures of necrotic scleral lesion before surgery. The conchal cartilage perichondrium graft was transplanted, and a conjunctival flap was created on the scleral lesion. The autologous perichondrium conchal cartilage graft was successful and visual outcome was stable in all patients, with no reports of graft failure or infection recurrence. In conclusion, autologous perichondrium conchal cartilage graft may be effective in surgical management of Pseudomonal infectious scleritis when non-surgical medical treatment is ineffective. Further studies in larger, diverse populations are warranted to establish the effectiveness of the procedure. Yonsei University College of Medicine 2015-11-01 2015-09-25 /pmc/articles/PMC4630068/ /pubmed/26446662 http://dx.doi.org/10.3349/ymj.2015.56.6.1738 Text en © Copyright: Yonsei University College of Medicine 2015 http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Yoo, Woong Sun
Kim, Che Ron
Kim, Byung Jae
Ahn, Seong Ki
Seo, Seong Wook
Yoo, Ji Myong
Kim, Seong Jae
Successful Treatment of Infectious Scleritis by Pseudomonas aeruginosa with Autologous Perichondrium Graft of Conchal Cartilage
title Successful Treatment of Infectious Scleritis by Pseudomonas aeruginosa with Autologous Perichondrium Graft of Conchal Cartilage
title_full Successful Treatment of Infectious Scleritis by Pseudomonas aeruginosa with Autologous Perichondrium Graft of Conchal Cartilage
title_fullStr Successful Treatment of Infectious Scleritis by Pseudomonas aeruginosa with Autologous Perichondrium Graft of Conchal Cartilage
title_full_unstemmed Successful Treatment of Infectious Scleritis by Pseudomonas aeruginosa with Autologous Perichondrium Graft of Conchal Cartilage
title_short Successful Treatment of Infectious Scleritis by Pseudomonas aeruginosa with Autologous Perichondrium Graft of Conchal Cartilage
title_sort successful treatment of infectious scleritis by pseudomonas aeruginosa with autologous perichondrium graft of conchal cartilage
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630068/
https://www.ncbi.nlm.nih.gov/pubmed/26446662
http://dx.doi.org/10.3349/ymj.2015.56.6.1738
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