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Preclinical evaluation of a urokinase plasminogen activator receptor-targeted nanoprobe in rhesus monkeys
PURPOSE: To translate a recombinant peptide containing the amino-terminal fragment (ATF) of urokinase plasminogen activator receptor-targeted magnetic iron oxide (IO) nanoparticles (uPAR-targeted human ATF-IONPs) into clinical applications, we conducted a pilot study to evaluate the toxicity and pha...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630189/ https://www.ncbi.nlm.nih.gov/pubmed/26604745 http://dx.doi.org/10.2147/IJN.S90587 |