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Preclinical evaluation of a urokinase plasminogen activator receptor-targeted nanoprobe in rhesus monkeys

PURPOSE: To translate a recombinant peptide containing the amino-terminal fragment (ATF) of urokinase plasminogen activator receptor-targeted magnetic iron oxide (IO) nanoparticles (uPAR-targeted human ATF-IONPs) into clinical applications, we conducted a pilot study to evaluate the toxicity and pha...

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Detalles Bibliográficos
Autores principales:	Chen, Yushu, Gong, Li, Gao, Ning, Liao, Jichun, Sun, Jiayu, Wang, Yuqing, Wang, Lei, Zhu, Pengjin, Fan, Qing, Wang, Yongqiang Andrew, Zeng, Wen, Mao, Hui, Yang, Lily, Gao, Fabao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2015
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630189/ https://www.ncbi.nlm.nih.gov/pubmed/26604745 http://dx.doi.org/10.2147/IJN.S90587

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