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Giant malignant peripheral nerve sheath tumor of thigh in an adolescent with neurofibromatosis type 1: a case report
Malignant peripheral nerve sheath tumors (MPNSTs) are rare sarcomas of children and adolescents, and they are aggressive tumors with a high rate of local recurrence. We present a 15-year-old boy with neurofibromatosis type 1 (NF1), who had a giant MPNST on the right thigh taking into account the ava...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630200/ https://www.ncbi.nlm.nih.gov/pubmed/26604833 http://dx.doi.org/10.2147/IMCRJ.S92015 |
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author | Tosun, Hacı Bayram Serbest, Sancar Turk, Bilge Aydın Gumustas, Seyit Ali Uludag, Abuzer |
author_facet | Tosun, Hacı Bayram Serbest, Sancar Turk, Bilge Aydın Gumustas, Seyit Ali Uludag, Abuzer |
author_sort | Tosun, Hacı Bayram |
collection | PubMed |
description | Malignant peripheral nerve sheath tumors (MPNSTs) are rare sarcomas of children and adolescents, and they are aggressive tumors with a high rate of local recurrence. We present a 15-year-old boy with neurofibromatosis type 1 (NF1), who had a giant MPNST on the right thigh taking into account the available literature. Diagnosis of MPNST may be delayed in NF1 patients due to confusion with a neurofibroma and/or a plexiform neurofibroma. Malignancy should be considered, especially in cases with big masses, with heterogeneous involvement, or in the presence of cysts or necrotic nodules. The aim of surgical treatment is complete surgical excision. |
format | Online Article Text |
id | pubmed-4630200 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Dove Medical Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-46302002015-11-24 Giant malignant peripheral nerve sheath tumor of thigh in an adolescent with neurofibromatosis type 1: a case report Tosun, Hacı Bayram Serbest, Sancar Turk, Bilge Aydın Gumustas, Seyit Ali Uludag, Abuzer Int Med Case Rep J Case Report Malignant peripheral nerve sheath tumors (MPNSTs) are rare sarcomas of children and adolescents, and they are aggressive tumors with a high rate of local recurrence. We present a 15-year-old boy with neurofibromatosis type 1 (NF1), who had a giant MPNST on the right thigh taking into account the available literature. Diagnosis of MPNST may be delayed in NF1 patients due to confusion with a neurofibroma and/or a plexiform neurofibroma. Malignancy should be considered, especially in cases with big masses, with heterogeneous involvement, or in the presence of cysts or necrotic nodules. The aim of surgical treatment is complete surgical excision. Dove Medical Press 2015-10-28 /pmc/articles/PMC4630200/ /pubmed/26604833 http://dx.doi.org/10.2147/IMCRJ.S92015 Text en © 2015 Tosun et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. |
spellingShingle | Case Report Tosun, Hacı Bayram Serbest, Sancar Turk, Bilge Aydın Gumustas, Seyit Ali Uludag, Abuzer Giant malignant peripheral nerve sheath tumor of thigh in an adolescent with neurofibromatosis type 1: a case report |
title | Giant malignant peripheral nerve sheath tumor of thigh in an adolescent with neurofibromatosis type 1: a case report |
title_full | Giant malignant peripheral nerve sheath tumor of thigh in an adolescent with neurofibromatosis type 1: a case report |
title_fullStr | Giant malignant peripheral nerve sheath tumor of thigh in an adolescent with neurofibromatosis type 1: a case report |
title_full_unstemmed | Giant malignant peripheral nerve sheath tumor of thigh in an adolescent with neurofibromatosis type 1: a case report |
title_short | Giant malignant peripheral nerve sheath tumor of thigh in an adolescent with neurofibromatosis type 1: a case report |
title_sort | giant malignant peripheral nerve sheath tumor of thigh in an adolescent with neurofibromatosis type 1: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630200/ https://www.ncbi.nlm.nih.gov/pubmed/26604833 http://dx.doi.org/10.2147/IMCRJ.S92015 |
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