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The Role of Vitamin D in Diabetes and Cardiovascular Disease: An Updated Review of the Literature

The dietary reference values for Vitamin D were set primarily considering its role in bone health, but with the discovery of Vitamin D receptors throughout body tissues, new links with other health conditions are now studied, such as for diabetes and cardiovascular diseases (CVD). This paper shall a...

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Detalles Bibliográficos
Autores principales: Papandreou, Dimitrios, Hamid, Zujaja-Tul-Noor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630385/
https://www.ncbi.nlm.nih.gov/pubmed/26576069
http://dx.doi.org/10.1155/2015/580474
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author Papandreou, Dimitrios
Hamid, Zujaja-Tul-Noor
author_facet Papandreou, Dimitrios
Hamid, Zujaja-Tul-Noor
author_sort Papandreou, Dimitrios
collection PubMed
description The dietary reference values for Vitamin D were set primarily considering its role in bone health, but with the discovery of Vitamin D receptors throughout body tissues, new links with other health conditions are now studied, such as for diabetes and cardiovascular diseases (CVD). This paper shall analyze and examine all new research studies carried out, especially in 2013–2015 regarding diabetes mellitus (DM) and cardiovascular diseases (CVD). Vast research has been carried out to establish strong relationship between Vitamin D serum levels, supplementation, diabetes, and CVD. However, the results from researches identified in this paper are disputable. Benefits of Vitamin D adequate levels were recognized from gestational period until later in disease development such as diabetes and/or CVD, but since not all studies are in agreement further investigation is suggested. Researches conducting large randomized controlled trials, exploring range of supplement doses, with variable baseline serum Vitamin D levels, and inclusion of array of associated parameters, are still required to conduct large-scale analysis and draw conclusion as a risk factor. Until then it is possible to conclude that maintenance of serum Vitamin D levels holds advantageous aspects in diabetic and cardiovascular conditions, and people should strive to attain them.
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spelling pubmed-46303852015-11-16 The Role of Vitamin D in Diabetes and Cardiovascular Disease: An Updated Review of the Literature Papandreou, Dimitrios Hamid, Zujaja-Tul-Noor Dis Markers Review Article The dietary reference values for Vitamin D were set primarily considering its role in bone health, but with the discovery of Vitamin D receptors throughout body tissues, new links with other health conditions are now studied, such as for diabetes and cardiovascular diseases (CVD). This paper shall analyze and examine all new research studies carried out, especially in 2013–2015 regarding diabetes mellitus (DM) and cardiovascular diseases (CVD). Vast research has been carried out to establish strong relationship between Vitamin D serum levels, supplementation, diabetes, and CVD. However, the results from researches identified in this paper are disputable. Benefits of Vitamin D adequate levels were recognized from gestational period until later in disease development such as diabetes and/or CVD, but since not all studies are in agreement further investigation is suggested. Researches conducting large randomized controlled trials, exploring range of supplement doses, with variable baseline serum Vitamin D levels, and inclusion of array of associated parameters, are still required to conduct large-scale analysis and draw conclusion as a risk factor. Until then it is possible to conclude that maintenance of serum Vitamin D levels holds advantageous aspects in diabetic and cardiovascular conditions, and people should strive to attain them. Hindawi Publishing Corporation 2015 2015-10-20 /pmc/articles/PMC4630385/ /pubmed/26576069 http://dx.doi.org/10.1155/2015/580474 Text en Copyright © 2015 D. Papandreou and Z.-T.-N. Hamid. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Papandreou, Dimitrios
Hamid, Zujaja-Tul-Noor
The Role of Vitamin D in Diabetes and Cardiovascular Disease: An Updated Review of the Literature
title The Role of Vitamin D in Diabetes and Cardiovascular Disease: An Updated Review of the Literature
title_full The Role of Vitamin D in Diabetes and Cardiovascular Disease: An Updated Review of the Literature
title_fullStr The Role of Vitamin D in Diabetes and Cardiovascular Disease: An Updated Review of the Literature
title_full_unstemmed The Role of Vitamin D in Diabetes and Cardiovascular Disease: An Updated Review of the Literature
title_short The Role of Vitamin D in Diabetes and Cardiovascular Disease: An Updated Review of the Literature
title_sort role of vitamin d in diabetes and cardiovascular disease: an updated review of the literature
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630385/
https://www.ncbi.nlm.nih.gov/pubmed/26576069
http://dx.doi.org/10.1155/2015/580474
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