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Mechanistic Contributions of Biological Cofactors in Islet Amyloid Polypeptide Amyloidogenesis

Type II diabetes mellitus is associated with the deposition of fibrillar aggregates in pancreatic islets. The major protein component of islet amyloids is the glucomodulatory hormone islet amyloid polypeptide (IAPP). Islet amyloid fibrils are virtually always associated with several biomolecules, in...

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Detalles Bibliográficos
Autores principales:	Nguyen, Phuong Trang, Andraka, Nagore, De Carufel, Carole Anne, Bourgault, Steve
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2015
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630397/ https://www.ncbi.nlm.nih.gov/pubmed/26576436 http://dx.doi.org/10.1155/2015/515307

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