Genotypes of Clinical and Environmental Isolates of Cryptococcus neoformans and Cryptococcus gattii in Korea

Multilocus sequence typing analysis was applied to determine the genotypes of 147 (137 clinical and 10 environmental) Cryptococcus neoformans and three clinical Cryptococcus gattii isolates from 1993 to 2014 in Korea. Among the 137 clinical isolates of C. neoformans, the most prevalent genotype was...

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Autores principales: Park, So Hae, Choi, Seok Cheol, Lee, Kyung Won, Kim, Mi-Na, Hwang, Soo Myung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Mycology 2015
Materias:
Research Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630447/
https://www.ncbi.nlm.nih.gov/pubmed/26539057
http://dx.doi.org/10.5941/MYCO.2015.43.3.360
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author Park, So Hae
Choi, Seok Cheol
Lee, Kyung Won
Kim, Mi-Na
Hwang, Soo Myung
author_facet Park, So Hae
Choi, Seok Cheol
Lee, Kyung Won
Kim, Mi-Na
Hwang, Soo Myung
author_sort Park, So Hae
collection PubMed
description Multilocus sequence typing analysis was applied to determine the genotypes of 147 (137 clinical and 10 environmental) Cryptococcus neoformans and three clinical Cryptococcus gattii isolates from 1993 to 2014 in Korea. Among the 137 clinical isolates of C. neoformans, the most prevalent genotype was ST5 (n = 131), followed by ST31 (n = 5) and ST127 (n = 1). Three C. gattii strains were identified as ST57, ST7, and ST113. All environmental isolates were identified as C. neoformans with two genotypes, ST5 (n = 7) and ST31 (n = 3). Our results show that C. neoformans isolates in Korea are genetically homogeneous, and represent a close genetic relationship between clinical and environmental isolates.
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spelling pubmed-46304472015-11-04 Genotypes of Clinical and Environmental Isolates of Cryptococcus neoformans and Cryptococcus gattii in Korea Park, So Hae Choi, Seok Cheol Lee, Kyung Won Kim, Mi-Na Hwang, Soo Myung Mycobiology Research Note Multilocus sequence typing analysis was applied to determine the genotypes of 147 (137 clinical and 10 environmental) Cryptococcus neoformans and three clinical Cryptococcus gattii isolates from 1993 to 2014 in Korea. Among the 137 clinical isolates of C. neoformans, the most prevalent genotype was ST5 (n = 131), followed by ST31 (n = 5) and ST127 (n = 1). Three C. gattii strains were identified as ST57, ST7, and ST113. All environmental isolates were identified as C. neoformans with two genotypes, ST5 (n = 7) and ST31 (n = 3). Our results show that C. neoformans isolates in Korea are genetically homogeneous, and represent a close genetic relationship between clinical and environmental isolates. The Korean Society of Mycology 2015-09 2015-09-30 /pmc/articles/PMC4630447/ /pubmed/26539057 http://dx.doi.org/10.5941/MYCO.2015.43.3.360 Text en © The Korean Society of Mycology http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Note
Park, So Hae
Choi, Seok Cheol
Lee, Kyung Won
Kim, Mi-Na
Hwang, Soo Myung
Genotypes of Clinical and Environmental Isolates of Cryptococcus neoformans and Cryptococcus gattii in Korea
title Genotypes of Clinical and Environmental Isolates of Cryptococcus neoformans and Cryptococcus gattii in Korea
title_full Genotypes of Clinical and Environmental Isolates of Cryptococcus neoformans and Cryptococcus gattii in Korea
title_fullStr Genotypes of Clinical and Environmental Isolates of Cryptococcus neoformans and Cryptococcus gattii in Korea
title_full_unstemmed Genotypes of Clinical and Environmental Isolates of Cryptococcus neoformans and Cryptococcus gattii in Korea
title_short Genotypes of Clinical and Environmental Isolates of Cryptococcus neoformans and Cryptococcus gattii in Korea
title_sort genotypes of clinical and environmental isolates of cryptococcus neoformans and cryptococcus gattii in korea
topic Research Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630447/
https://www.ncbi.nlm.nih.gov/pubmed/26539057
http://dx.doi.org/10.5941/MYCO.2015.43.3.360
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