Application of hypersensitivity skin testing in chemotherapy-induced pneumonitis

Skin testing has been utilised to determine the culprit allergenic agent in drug reactions. Its application in the setting of hypersensitivity reaction relating to combination chemotherapeutic regimens may help identify the causative drug, allowing drug that is safe to be continued and avoiding limi...

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Detalles Bibliográficos
Autores principales: Kuo, James C, Hawkins, Carolyn A, Yip, Desmond
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Asia Pacific Association of Allergy, Asthma and Clinical Immunology 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630463/
https://www.ncbi.nlm.nih.gov/pubmed/26539407
http://dx.doi.org/10.5415/apallergy.2015.5.4.234
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author Kuo, James C
Hawkins, Carolyn A
Yip, Desmond
author_facet Kuo, James C
Hawkins, Carolyn A
Yip, Desmond
author_sort Kuo, James C
collection PubMed
description Skin testing has been utilised to determine the culprit allergenic agent in drug reactions. Its application in the setting of hypersensitivity reaction relating to combination chemotherapeutic regimens may help identify the causative drug, allowing drug that is safe to be continued and avoiding limiting treatment options for patients. We report what we believe to be the first published case of hypersensitivity skin testing for gemcitabine-induced pneumonitis in a patient with metastatic leiomyosarcoma and another case of docetaxel-induced pneumonitis in a patient with metastatic HER2-positive breast cancer.
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spelling pubmed-46304632015-11-04 Application of hypersensitivity skin testing in chemotherapy-induced pneumonitis Kuo, James C Hawkins, Carolyn A Yip, Desmond Asia Pac Allergy Case Report Skin testing has been utilised to determine the culprit allergenic agent in drug reactions. Its application in the setting of hypersensitivity reaction relating to combination chemotherapeutic regimens may help identify the causative drug, allowing drug that is safe to be continued and avoiding limiting treatment options for patients. We report what we believe to be the first published case of hypersensitivity skin testing for gemcitabine-induced pneumonitis in a patient with metastatic leiomyosarcoma and another case of docetaxel-induced pneumonitis in a patient with metastatic HER2-positive breast cancer. Asia Pacific Association of Allergy, Asthma and Clinical Immunology 2015-10 2015-10-28 /pmc/articles/PMC4630463/ /pubmed/26539407 http://dx.doi.org/10.5415/apallergy.2015.5.4.234 Text en Copyright © 2015. Asia Pacific Association of Allergy, Asthma and Clinical Immunology. http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Kuo, James C
Hawkins, Carolyn A
Yip, Desmond
Application of hypersensitivity skin testing in chemotherapy-induced pneumonitis
title Application of hypersensitivity skin testing in chemotherapy-induced pneumonitis
title_full Application of hypersensitivity skin testing in chemotherapy-induced pneumonitis
title_fullStr Application of hypersensitivity skin testing in chemotherapy-induced pneumonitis
title_full_unstemmed Application of hypersensitivity skin testing in chemotherapy-induced pneumonitis
title_short Application of hypersensitivity skin testing in chemotherapy-induced pneumonitis
title_sort application of hypersensitivity skin testing in chemotherapy-induced pneumonitis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630463/
https://www.ncbi.nlm.nih.gov/pubmed/26539407
http://dx.doi.org/10.5415/apallergy.2015.5.4.234
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