Cargando…
Gender Differences in Depressive Symptom Profile: Results from Nationwide General Population Surveys in Korea
This study investigated gender differences in symptom profiles of major depressive disorder (MDD) in the Korean general population. Data were pooled from the series of nationwide Korean Epidemiologic Catchment Area surveys conducted in 2001, 2006 and 2011, respectively. Of the 18,807 participants, 5...
Autores principales: | , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Academy of Medical Sciences
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630484/ https://www.ncbi.nlm.nih.gov/pubmed/26539012 http://dx.doi.org/10.3346/jkms.2015.30.11.1659 |
_version_ | 1782398715468709888 |
---|---|
author | Kim, Ji-Hyun Cho, Maeng Je Hong, Jin Pyo Bae, Jae Nam Cho, Seong-Jin Hahm, Bong-Jin Lee, Dong-Woo Park, Jong-Ik Lee, Jun-Young Jeon, Hong Jin Chang, Sung Man |
author_facet | Kim, Ji-Hyun Cho, Maeng Je Hong, Jin Pyo Bae, Jae Nam Cho, Seong-Jin Hahm, Bong-Jin Lee, Dong-Woo Park, Jong-Ik Lee, Jun-Young Jeon, Hong Jin Chang, Sung Man |
author_sort | Kim, Ji-Hyun |
collection | PubMed |
description | This study investigated gender differences in symptom profiles of major depressive disorder (MDD) in the Korean general population. Data were pooled from the series of nationwide Korean Epidemiologic Catchment Area surveys conducted in 2001, 2006 and 2011, respectively. Of the 18,807 participants, 507 (397 women and 110 men) were diagnosed with MDD within the prior 12 months. In agreement with previous studies, women with MDD appeared to be more vulnerable to experiencing atypical depressive episodes defined as depression with two or more symptoms of fatigue, increased appetite and hypersomnia (P < 0.001). In terms of individual symptoms, female gender was significantly related with higher prevalence of fatigue (P = 0.008), hypersomnia (P = 0.001), noticeable psychomotor retardation (P = 0.029) and suicidal attempts (P = 0.016) with adjustment for birth cohort effect, partner status, and employment status. In the same analysis, men with MDD appeared more vulnerable to decreased libido than women (P = 0.009). This is the first report to demonstrate gender differences in symptomatology of MDD in the general Korean population, and the results are comparable to previous investigations from western societies. Assumingly, the intercultural similarity in female preponderance to atypical depression might reflect the common biological construct underlying the gender difference in mechanism of MDD. In clinical settings, gender differences of MDD should be carefully considered, because these features could be related with treatment response and drug side effects. |
format | Online Article Text |
id | pubmed-4630484 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | The Korean Academy of Medical Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-46304842015-11-04 Gender Differences in Depressive Symptom Profile: Results from Nationwide General Population Surveys in Korea Kim, Ji-Hyun Cho, Maeng Je Hong, Jin Pyo Bae, Jae Nam Cho, Seong-Jin Hahm, Bong-Jin Lee, Dong-Woo Park, Jong-Ik Lee, Jun-Young Jeon, Hong Jin Chang, Sung Man J Korean Med Sci Original Article This study investigated gender differences in symptom profiles of major depressive disorder (MDD) in the Korean general population. Data were pooled from the series of nationwide Korean Epidemiologic Catchment Area surveys conducted in 2001, 2006 and 2011, respectively. Of the 18,807 participants, 507 (397 women and 110 men) were diagnosed with MDD within the prior 12 months. In agreement with previous studies, women with MDD appeared to be more vulnerable to experiencing atypical depressive episodes defined as depression with two or more symptoms of fatigue, increased appetite and hypersomnia (P < 0.001). In terms of individual symptoms, female gender was significantly related with higher prevalence of fatigue (P = 0.008), hypersomnia (P = 0.001), noticeable psychomotor retardation (P = 0.029) and suicidal attempts (P = 0.016) with adjustment for birth cohort effect, partner status, and employment status. In the same analysis, men with MDD appeared more vulnerable to decreased libido than women (P = 0.009). This is the first report to demonstrate gender differences in symptomatology of MDD in the general Korean population, and the results are comparable to previous investigations from western societies. Assumingly, the intercultural similarity in female preponderance to atypical depression might reflect the common biological construct underlying the gender difference in mechanism of MDD. In clinical settings, gender differences of MDD should be carefully considered, because these features could be related with treatment response and drug side effects. The Korean Academy of Medical Sciences 2015-11 2015-10-16 /pmc/articles/PMC4630484/ /pubmed/26539012 http://dx.doi.org/10.3346/jkms.2015.30.11.1659 Text en © 2015 The Korean Academy of Medical Sciences. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Kim, Ji-Hyun Cho, Maeng Je Hong, Jin Pyo Bae, Jae Nam Cho, Seong-Jin Hahm, Bong-Jin Lee, Dong-Woo Park, Jong-Ik Lee, Jun-Young Jeon, Hong Jin Chang, Sung Man Gender Differences in Depressive Symptom Profile: Results from Nationwide General Population Surveys in Korea |
title | Gender Differences in Depressive Symptom Profile: Results from Nationwide General Population Surveys in Korea |
title_full | Gender Differences in Depressive Symptom Profile: Results from Nationwide General Population Surveys in Korea |
title_fullStr | Gender Differences in Depressive Symptom Profile: Results from Nationwide General Population Surveys in Korea |
title_full_unstemmed | Gender Differences in Depressive Symptom Profile: Results from Nationwide General Population Surveys in Korea |
title_short | Gender Differences in Depressive Symptom Profile: Results from Nationwide General Population Surveys in Korea |
title_sort | gender differences in depressive symptom profile: results from nationwide general population surveys in korea |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630484/ https://www.ncbi.nlm.nih.gov/pubmed/26539012 http://dx.doi.org/10.3346/jkms.2015.30.11.1659 |
work_keys_str_mv | AT kimjihyun genderdifferencesindepressivesymptomprofileresultsfromnationwidegeneralpopulationsurveysinkorea AT chomaengje genderdifferencesindepressivesymptomprofileresultsfromnationwidegeneralpopulationsurveysinkorea AT hongjinpyo genderdifferencesindepressivesymptomprofileresultsfromnationwidegeneralpopulationsurveysinkorea AT baejaenam genderdifferencesindepressivesymptomprofileresultsfromnationwidegeneralpopulationsurveysinkorea AT choseongjin genderdifferencesindepressivesymptomprofileresultsfromnationwidegeneralpopulationsurveysinkorea AT hahmbongjin genderdifferencesindepressivesymptomprofileresultsfromnationwidegeneralpopulationsurveysinkorea AT leedongwoo genderdifferencesindepressivesymptomprofileresultsfromnationwidegeneralpopulationsurveysinkorea AT parkjongik genderdifferencesindepressivesymptomprofileresultsfromnationwidegeneralpopulationsurveysinkorea AT leejunyoung genderdifferencesindepressivesymptomprofileresultsfromnationwidegeneralpopulationsurveysinkorea AT jeonhongjin genderdifferencesindepressivesymptomprofileresultsfromnationwidegeneralpopulationsurveysinkorea AT changsungman genderdifferencesindepressivesymptomprofileresultsfromnationwidegeneralpopulationsurveysinkorea |