(13)C-tryptophan breath test detects increased catabolic turnover of tryptophan along the kynurenine pathway in patients with major depressive disorder

Altered tryptophan–kynurenine (KYN) metabolism has been implicated in major depressive disorder (MDD). The l-[1-(13)C]tryptophan breath test ((13)C-TBT) is a noninvasive, stable-isotope tracer method in which exhaled (13)CO(2) is attributable to tryptophan catabolism via the KYN pathway. We included...

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Detalles Bibliográficos
Autores principales: Teraishi, Toshiya, Hori, Hiroaki, Sasayama, Daimei, Matsuo, Junko, Ogawa, Shintaro, Ota, Miho, Hattori, Kotaro, Kajiwara, Masahiro, Higuchi, Teruhiko, Kunugi, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630584/
https://www.ncbi.nlm.nih.gov/pubmed/26524975
http://dx.doi.org/10.1038/srep15994

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