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CD11b deficiency suppresses intestinal tumor growth by reducing myeloid cell recruitment

Mac-1 (CD11b) is expressed on bone marrow-derived immune cells. CD11b binds to ligands to regulate leukocyte adhesion and migration across the endothelium or epithelium. Here, we employed CD11b knockout mice and an Apc(Min/+) spontaneous intestinal adenoma mouse model to clarify the function of CD11...

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Detalles Bibliográficos
Autores principales:	Zhang, Qian-Qian, Hu, Xi-Wen, Liu, Yi-Long, Ye, Zhi-Jin, Gui, Yi-He, Zhou, Da-Lei, Qi, Cui-Ling, He, Xiao-Dong, Wang, Honglin, Wang, Li-Jing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630647/ https://www.ncbi.nlm.nih.gov/pubmed/26526388 http://dx.doi.org/10.1038/srep15948

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