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Determining composition of micron-scale protein deposits in neurodegenerative disease by spatially targeted optical microproteomics

Spatially targeted optical microproteomics (STOMP) is a novel proteomics technique for interrogating micron-scale regions of interest (ROIs) in mammalian tissue, with no requirement for genetic manipulation. Methanol or formalin-fixed specimens are stained with fluorescent dyes or antibodies to visu...

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Detalles Bibliográficos
Autores principales:	Hadley, Kevin C, Rakhit, Rishi, Guo, Hongbo, Sun, Yulong, Jonkman, James EN, McLaurin, Joanne, Hazrati, Lili-Naz, Emili, Andrew, Chakrabartty, Avijit
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2015
Materias:	Biochemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630677/ https://www.ncbi.nlm.nih.gov/pubmed/26418743 http://dx.doi.org/10.7554/eLife.09579

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