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The antioxidant master glutathione and periodontal health
Glutathione, considered to be the master antioxidant (AO), is the most-important redox regulator that controls inflammatory processes, and thus damage to the periodontium. Periodontitis patients have reduced total AO capacity in whole saliva, and lower concentrations of reduced glutathione (GSH) in...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630702/ https://www.ncbi.nlm.nih.gov/pubmed/26604952 |
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author | Bains, Vivek Kumar Bains, Rhythm |
author_facet | Bains, Vivek Kumar Bains, Rhythm |
author_sort | Bains, Vivek Kumar |
collection | PubMed |
description | Glutathione, considered to be the master antioxidant (AO), is the most-important redox regulator that controls inflammatory processes, and thus damage to the periodontium. Periodontitis patients have reduced total AO capacity in whole saliva, and lower concentrations of reduced glutathione (GSH) in serum and gingival crevicular fluid, and periodontal therapy restores the redox balance. Therapeutic considerations for the adjunctive use of glutathione in management of periodontitis, in limiting the tissue damage associated with oxidative stress, and enhancing wound healing cannot be underestimated, but need to be evaluated further through multi-centered randomized controlled trials. |
format | Online Article Text |
id | pubmed-4630702 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-46307022015-11-24 The antioxidant master glutathione and periodontal health Bains, Vivek Kumar Bains, Rhythm Dent Res J (Isfahan) Review Article Glutathione, considered to be the master antioxidant (AO), is the most-important redox regulator that controls inflammatory processes, and thus damage to the periodontium. Periodontitis patients have reduced total AO capacity in whole saliva, and lower concentrations of reduced glutathione (GSH) in serum and gingival crevicular fluid, and periodontal therapy restores the redox balance. Therapeutic considerations for the adjunctive use of glutathione in management of periodontitis, in limiting the tissue damage associated with oxidative stress, and enhancing wound healing cannot be underestimated, but need to be evaluated further through multi-centered randomized controlled trials. Medknow Publications & Media Pvt Ltd 2015 /pmc/articles/PMC4630702/ /pubmed/26604952 Text en Copyright: © Dental Research Journal http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution NonCommercial ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non commercially, as long as the author is credited and the new creations are licensed under the identical terms. |
spellingShingle | Review Article Bains, Vivek Kumar Bains, Rhythm The antioxidant master glutathione and periodontal health |
title | The antioxidant master glutathione and periodontal health |
title_full | The antioxidant master glutathione and periodontal health |
title_fullStr | The antioxidant master glutathione and periodontal health |
title_full_unstemmed | The antioxidant master glutathione and periodontal health |
title_short | The antioxidant master glutathione and periodontal health |
title_sort | antioxidant master glutathione and periodontal health |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630702/ https://www.ncbi.nlm.nih.gov/pubmed/26604952 |
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