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Comparative analysis of detecting cervical lymph node metastasis with fine needle aspiration cytology

OBJECTIVES: We correlated the results of cervical lymph node (LN) status by T-tumor size, N-nodal metastasis, M-distant metastasis (TNM) staging, and fine needle aspiration cytology (FNAC) in oral cancer patients to assess the discrepancy index (DI) between nodal metastasis (N) and FNAC results of c...

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Autores principales: Shakeel, Mohammed Kamran, Daniel, Mariappan Jonathan, Srinivasan, Subramaniam Vasudevan, Koliyan, Ramadoss, Kumar, Jimsha Vannathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630768/
https://www.ncbi.nlm.nih.gov/pubmed/26604624
http://dx.doi.org/10.4103/0976-9668.166050
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author Shakeel, Mohammed Kamran
Daniel, Mariappan Jonathan
Srinivasan, Subramaniam Vasudevan
Koliyan, Ramadoss
Kumar, Jimsha Vannathan
author_facet Shakeel, Mohammed Kamran
Daniel, Mariappan Jonathan
Srinivasan, Subramaniam Vasudevan
Koliyan, Ramadoss
Kumar, Jimsha Vannathan
author_sort Shakeel, Mohammed Kamran
collection PubMed
description OBJECTIVES: We correlated the results of cervical lymph node (LN) status by T-tumor size, N-nodal metastasis, M-distant metastasis (TNM) staging, and fine needle aspiration cytology (FNAC) in oral cancer patients to assess the discrepancy index (DI) between nodal metastasis (N) and FNAC results of cervicofacial LNs. MATERIALS AND METHODS: A total of 63 patients (29 females and 34 males) aged from 30 to 85 years were included in our study. Cervical LN status through TNM staging and FNAC results were matched and DI was calculated. RESULTS: DI in case of nodal status was 64.10% and 43.47% for TNMN1 and N2, respectively, indicating that tendency for observation of positive result on FNAC increased from N1 to N2. CONCLUSION: Hence, we suggest that relying solely on clinical examination and routine diagnostic tests like FNAC may not be appropriate and additional diagnostic imaging modalities should be considered.
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spelling pubmed-46307682015-11-24 Comparative analysis of detecting cervical lymph node metastasis with fine needle aspiration cytology Shakeel, Mohammed Kamran Daniel, Mariappan Jonathan Srinivasan, Subramaniam Vasudevan Koliyan, Ramadoss Kumar, Jimsha Vannathan J Nat Sci Biol Med Original Article OBJECTIVES: We correlated the results of cervical lymph node (LN) status by T-tumor size, N-nodal metastasis, M-distant metastasis (TNM) staging, and fine needle aspiration cytology (FNAC) in oral cancer patients to assess the discrepancy index (DI) between nodal metastasis (N) and FNAC results of cervicofacial LNs. MATERIALS AND METHODS: A total of 63 patients (29 females and 34 males) aged from 30 to 85 years were included in our study. Cervical LN status through TNM staging and FNAC results were matched and DI was calculated. RESULTS: DI in case of nodal status was 64.10% and 43.47% for TNMN1 and N2, respectively, indicating that tendency for observation of positive result on FNAC increased from N1 to N2. CONCLUSION: Hence, we suggest that relying solely on clinical examination and routine diagnostic tests like FNAC may not be appropriate and additional diagnostic imaging modalities should be considered. Medknow Publications & Media Pvt Ltd 2015-08 /pmc/articles/PMC4630768/ /pubmed/26604624 http://dx.doi.org/10.4103/0976-9668.166050 Text en Copyright: © Journal of Natural Science, Biology and Medicine http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Original Article
Shakeel, Mohammed Kamran
Daniel, Mariappan Jonathan
Srinivasan, Subramaniam Vasudevan
Koliyan, Ramadoss
Kumar, Jimsha Vannathan
Comparative analysis of detecting cervical lymph node metastasis with fine needle aspiration cytology
title Comparative analysis of detecting cervical lymph node metastasis with fine needle aspiration cytology
title_full Comparative analysis of detecting cervical lymph node metastasis with fine needle aspiration cytology
title_fullStr Comparative analysis of detecting cervical lymph node metastasis with fine needle aspiration cytology
title_full_unstemmed Comparative analysis of detecting cervical lymph node metastasis with fine needle aspiration cytology
title_short Comparative analysis of detecting cervical lymph node metastasis with fine needle aspiration cytology
title_sort comparative analysis of detecting cervical lymph node metastasis with fine needle aspiration cytology
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630768/
https://www.ncbi.nlm.nih.gov/pubmed/26604624
http://dx.doi.org/10.4103/0976-9668.166050
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