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Subtractive assembly for comparative metagenomics, and its application to type 2 diabetes metagenomes

Comparative metagenomics remains challenging due to the size and complexity of metagenomic datasets. Here we introduce subtractive assembly, a de novo assembly approach for comparative metagenomics that directly assembles only the differential reads that distinguish between two groups of metagenomes...

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Detalles Bibliográficos
Autores principales: Wang, Mingjie, Doak, Thomas G., Ye, Yuzhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630832/
https://www.ncbi.nlm.nih.gov/pubmed/26527161
http://dx.doi.org/10.1186/s13059-015-0804-0