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Toremifene, a selective estrogen receptor modulator, significantly improved biochemical recurrence in bone metastatic prostate cancer: a randomized controlled phase II a trial
BACKGROUNDS: Durability of androgen-deprivation therapy (ADT) for prostate cancer (PC) is limited. Additional selective estrogen receptor modulators (SERMs) may prolong the durability of ADT, because androgen and estrogen signaling drive PC progression. METHODS: Men with treatment-naïve bone metasta...
Autores principales: | Fujimura, Tetsuya, Takahashi, Satoru, Kume, Haruki, Urano, Tomohiko, Takayama, Kenichi, Yamada, Yuta, Suzuki, Motofumi, Fukuhara, Hiroshi, Nakagawa, Tohru, Inoue, Satoshi, Homma, Yukio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630884/ https://www.ncbi.nlm.nih.gov/pubmed/26526623 http://dx.doi.org/10.1186/s12885-015-1871-z |
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