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Time depended Bcl-2 inhibition might be useful for a targeted drug therapy
BACKGROUND: Over expression of Bcl-2 is frequently observed in several types of cancers and it is one of the prognostic markers in breast cancer. The importance of the Bcl-2 protein as ideal therapeutic target is the dual role of inhibiting apoptosis and autophagy-mediated cell death. Thus, the bcl-...
Autores principales: | Talaiezadeh, Abdolhassan, jalali, Fateme, Galehdari, Hamid, Khodadadi, Ali |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630962/ https://www.ncbi.nlm.nih.gov/pubmed/26535028 http://dx.doi.org/10.1186/s12935-015-0254-5 |
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