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Leptin and adiponectin DNA methylation levels in adipose tissues and blood cells are associated with BMI, waist girth and LDL-cholesterol levels in severely obese men and women
BACKGROUND: Leptin (LEP) and adiponectin (ADIPOQ) genes encode adipokines that are mainly secreted by adipose tissues, involved in energy balance and suspected to play a role in the pathways linking adiposity to impaired glucose and insulin homeostasis. We have thus hypothesized that LEP and ADIPOQ...
Autores principales: | Houde, Andrée-Anne, Légaré, Cécilia, Biron, Simon, Lescelleur, Odette, Biertho, Laurent, Marceau, Simon, Tchernof, André, Vohl, Marie-Claude, Hivert, Marie-France, Bouchard, Luigi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631085/ https://www.ncbi.nlm.nih.gov/pubmed/25929254 http://dx.doi.org/10.1186/s12881-015-0174-1 |
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