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Longevity GWAS Using the Drosophila Genetic Reference Panel

We used 197 Drosophila melanogaster Genetic Reference Panel (DGRP) lines to perform a genome-wide association analysis for virgin female lifespan, using ~2M common single nucleotide polymorphisms (SNPs). We found considerable genetic variation in lifespan in the DGRP, with a broad-sense heritability...

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Detalles Bibliográficos
Autores principales:	Ivanov, Dobril K., Escott-Price, Valentina, Ziehm, Matthias, Magwire, Michael M., Mackay, Trudy F. C., Partridge, Linda, Thornton, Janet M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2015
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631106/ https://www.ncbi.nlm.nih.gov/pubmed/25922346 http://dx.doi.org/10.1093/gerona/glv047

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