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Favipiravir inhibits acetaminophen sulfate formation but minimally affects systemic pharmacokinetics of acetaminophen

AIMS: The antiviral agent favipiravir is likely to be co-prescribed with acetaminophen (paracetamol). The present study evaluated the possiblility of a pharmacokinetic interaction between favipiravir and acetaminophen, in vitro and in vivo. METHODS: The effect of favipivir on the transformation of a...

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Detalles Bibliográficos
Autores principales:	Zhao, Yanli, Harmatz, Jerold S, Epstein, Carol R, Nakagawa, Yukako, Kurosaki, Chie, Nakamura, Tetsuro, Kadota, Takumi, Giesing, Dennis, Court, Michael H, Greenblatt, David J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Ltd 2015
Materias:	Drug Interactions
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631180/ https://www.ncbi.nlm.nih.gov/pubmed/25808818 http://dx.doi.org/10.1111/bcp.12644

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