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Haemophagocytic lymphohistiocytosis in inflammatory bowel disease with virus infection
Patients with inflammatory bowel disease (IBD) are at risk of developing haemophagocytic lymphohistiocytosis (HLH) because of chronic systemic inflammation as well as exposure to immunosuppressive medications. The two main causes of HLH in IBD patients are infection with cytomegalovirus and Epstein-...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Termedia Publishing House
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631275/ https://www.ncbi.nlm.nih.gov/pubmed/26557937 http://dx.doi.org/10.5114/pg.2015.48995 |
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author | Li, Yuan Xia, Xuefeng Zhang, Jing Song, Zhiqiang Zhou, Liya Zhang, Yaopeng Huang, Yonghui Shi, Yanyan Quigley, Eamonn M.M. Ding, Shigang |
author_facet | Li, Yuan Xia, Xuefeng Zhang, Jing Song, Zhiqiang Zhou, Liya Zhang, Yaopeng Huang, Yonghui Shi, Yanyan Quigley, Eamonn M.M. Ding, Shigang |
author_sort | Li, Yuan |
collection | PubMed |
description | Patients with inflammatory bowel disease (IBD) are at risk of developing haemophagocytic lymphohistiocytosis (HLH) because of chronic systemic inflammation as well as exposure to immunosuppressive medications. The two main causes of HLH in IBD patients are infection with cytomegalovirus and Epstein-Barr virus. Patients with Crohn's disease are more susceptible to HLH than those with ulcerative colitis. The majority of cases are seen in people receiving an immunosuppressive regimen that included thiopurines. |
format | Online Article Text |
id | pubmed-4631275 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Termedia Publishing House |
record_format | MEDLINE/PubMed |
spelling | pubmed-46312752015-11-10 Haemophagocytic lymphohistiocytosis in inflammatory bowel disease with virus infection Li, Yuan Xia, Xuefeng Zhang, Jing Song, Zhiqiang Zhou, Liya Zhang, Yaopeng Huang, Yonghui Shi, Yanyan Quigley, Eamonn M.M. Ding, Shigang Prz Gastroenterol Review Paper Patients with inflammatory bowel disease (IBD) are at risk of developing haemophagocytic lymphohistiocytosis (HLH) because of chronic systemic inflammation as well as exposure to immunosuppressive medications. The two main causes of HLH in IBD patients are infection with cytomegalovirus and Epstein-Barr virus. Patients with Crohn's disease are more susceptible to HLH than those with ulcerative colitis. The majority of cases are seen in people receiving an immunosuppressive regimen that included thiopurines. Termedia Publishing House 2015-10-02 2015 /pmc/articles/PMC4631275/ /pubmed/26557937 http://dx.doi.org/10.5114/pg.2015.48995 Text en Copyright © 2015 Termedia http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial 3.0 Unported License, permitting all non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Paper Li, Yuan Xia, Xuefeng Zhang, Jing Song, Zhiqiang Zhou, Liya Zhang, Yaopeng Huang, Yonghui Shi, Yanyan Quigley, Eamonn M.M. Ding, Shigang Haemophagocytic lymphohistiocytosis in inflammatory bowel disease with virus infection |
title | Haemophagocytic lymphohistiocytosis in inflammatory bowel disease with virus infection |
title_full | Haemophagocytic lymphohistiocytosis in inflammatory bowel disease with virus infection |
title_fullStr | Haemophagocytic lymphohistiocytosis in inflammatory bowel disease with virus infection |
title_full_unstemmed | Haemophagocytic lymphohistiocytosis in inflammatory bowel disease with virus infection |
title_short | Haemophagocytic lymphohistiocytosis in inflammatory bowel disease with virus infection |
title_sort | haemophagocytic lymphohistiocytosis in inflammatory bowel disease with virus infection |
topic | Review Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631275/ https://www.ncbi.nlm.nih.gov/pubmed/26557937 http://dx.doi.org/10.5114/pg.2015.48995 |
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