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Comparative Genome of GK and Wistar Rats Reveals Genetic Basis of Type 2 Diabetes
The Goto-Kakizaki (GK) rat, which has been developed by repeated inbreeding of glucose-intolerant Wistar rats, is the most widely studied rat model for Type 2 diabetes (T2D). However, the detailed genetic background of T2D phenotype in GK rats is still largely unknown. We report a survey of T2D susc...
Autores principales: | Liu, Tiancheng, Li, Hong, Ding, Guohui, Wang, Zhen, Chen, Yunqin, Liu, Lei, Li, Yuanyuan, Li, Yixue |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631338/ https://www.ncbi.nlm.nih.gov/pubmed/26529237 http://dx.doi.org/10.1371/journal.pone.0141859 |
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