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Identification and Characterization of the Interaction Site between cFLIP(L) and Calmodulin

Overexpression of the cellular FLICE-like inhibitory protein (cFLIP) has been reported in a number of tumor types. As an inactive procaspase-8 homologue, cFLIP is recruited to the intracellular assembly known as the Death Inducing Signaling Complex (DISC) where it inhibits apoptosis, leading to canc...

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Detalles Bibliográficos
Autores principales:	Gaidos, Gabriel, Panaitiu, Alexandra E., Guo, Bingqian, Pellegrini, Maria, Mierke, Dale F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631386/ https://www.ncbi.nlm.nih.gov/pubmed/26529318 http://dx.doi.org/10.1371/journal.pone.0141692

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