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Mutant Huntingtin Does Not Affect the Intrinsic Phenotype of Human Huntington’s Disease T Lymphocytes

Huntington’s disease is a fatal neurodegenerative condition caused by a CAG repeat expansion in the huntingtin gene. The peripheral innate immune system is dysregulated in Huntington’s disease and may contribute to its pathogenesis. However, it is not clear whether or to what extent the adaptive imm...

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Detalles Bibliográficos
Autores principales:	Miller, James R. C., Träger, Ulrike, Andre, Ralph, Tabrizi, Sarah J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631523/ https://www.ncbi.nlm.nih.gov/pubmed/26529236 http://dx.doi.org/10.1371/journal.pone.0141793

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